Effects of Some Silver Salts on the Eye

Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review

“…In rabbits, different silver salts were applied to the eyes. All investigated salts, namely, silver nitrate, silver ammonium nitrate, silver ammonium sulfate, and silver ammonium lactate, were found to irritate eyes (Calvery, 1941). Further, a 100 mg of 10 nm silver nanoparticles in 21% solution was applied to one eye of rabbits (~5 mg silver/cm 2 ).…”

Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review

“…In rabbits, different silver salts were applied to the eyes. All investigated salts, namely, silver nitrate, silver ammonium nitrate, silver ammonium sulfate, and silver ammonium lactate, were found to irritate eyes (Calvery, 1941). Further, a 100 mg of 10 nm silver nanoparticles in 21% solution was applied to one eye of rabbits (~5 mg silver/cm 2 ).…”

Cytotoxic, Apoptotic, and Oxidative Effects of Preserved and Preservative-Free Brimonidine in a Corneal Epithelial Cell Line

“…Today, data on silver uptake and metabolism are not well documented, but it is known to cause ocular irritation. 35 Calvery et al 36 studied the effects of silver salts on rabbit eyes and found that all the salts were irritative. We believe that the contamination of the preservative-free eye drops used in our study with silver ions implemented in the cap design may be related to the results we obtained.…”

Ocular Argyrosis Mimicking Conjunctival Melanoma

“…1 Ocular argyrosis, however, is a specific form of argyria in which silver deposits accumulate in the region of the eye. 2 …”

Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review

“…In rabbits, different silver salts were applied to the eyes. All investigated salts, namely, silver nitrate, silver ammonium nitrate, silver ammonium sulfate, and silver ammonium lactate, were found to irritate eyes (Calvery, 1941). Further, a 100 mg of 10 nm silver nanoparticles in 21% solution was applied to one eye of rabbits (~5 mg silver/cm 2 ).…”

Cytotoxic, Apoptotic, and Oxidative Effects of Preserved and Preservative-Free Brimonidine in a Corneal Epithelial Cell Line

“…Today, data on silver uptake and metabolism are not well documented, but it is known to cause ocular irritation. 35 Calvery et al 36 studied the effects of silver salts on rabbit eyes and found that all the salts were irritative. We believe that the contamination of the preservative-free eye drops used in our study with silver ions implemented in the cap design may be related to the results we obtained.…”

Ocular Argyrosis Mimicking Conjunctival Melanoma

“…1 Ocular argyrosis, however, is a specific form of argyria in which silver deposits accumulate in the region of the eye. 2 …”

Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review

“…In rabbits, different silver salts were applied to the eyes. All investigated salts, namely, silver nitrate, silver ammonium nitrate, silver ammonium sulfate, and silver ammonium lactate, were found to irritate eyes (Calvery, 1941). Further, a 100 mg of 10 nm silver nanoparticles in 21% solution was applied to one eye of rabbits (~5 mg silver/cm 2 ).…”

Cytotoxic, Apoptotic, and Oxidative Effects of Preserved and Preservative-Free Brimonidine in a Corneal Epithelial Cell Line

“…Today, data on silver uptake and metabolism are not well documented, but it is known to cause ocular irritation. 35 Calvery et al 36 studied the effects of silver salts on rabbit eyes and found that all the salts were irritative. We believe that the contamination of the preservative-free eye drops used in our study with silver ions implemented in the cap design may be related to the results we obtained.…”

Ocular Argyrosis Mimicking Conjunctival Melanoma

“…1 Ocular argyrosis, however, is a specific form of argyria in which silver deposits accumulate in the region of the eye. 2 …”