Effects of protein supplementation and parasympathetic stimulation with slaframine on utilization of low quality roughage fed to goats and sheep

Gaskins, H. Rex; Croom, W. J.; Eys, J.E. van; Johnson, William L.; Hagler, W. M.

doi:10.1016/0921-4488(90)90051-7

Cited by 14 publications

(3 citation statements)

References 18 publications

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“…Consistent with this finding, 30 pg of S F k g BW i.m. for 56 d decreased feed intake and growth of wethers and goats (Gaskins et al, 1990). The authors hypothesized that the decreased feed intake may have been related to the amount of SF administered, because smaller doses did not elicit similar responses.…”

Section: Discussionmentioning

confidence: 99%

The effect of daily slaframine injection of salivary score, feed intake, ruminal pH, and circulating concentrations of somatotropin and insulin-like growth factor I1

Hibbard

et al. 1995

Journal of Animal Science

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In a randomized complete block design with repeated measures, ruminally cannulated crossbred beef steers (n = 24; 279 +/- 3.2 kg) had ad libitum access to a 90% concentrate diet and were injected daily with slaframine dichloride (SF) at doses of 0, 30, or 60 micrograms SF free-base/kg BW. On d 1, 2, 7, 14, and 21, salivary scores were determined hourly from -2 to 8 h relative to injection (0 h), and ruminal pH was measured at 0, 4, and 8 h. Feed intake was measured daily. Serum concentrations of somatotropin (ST) were measured in samples collected at 20-min intervals from -40 min to 8 h on d 2, 7, 14, and 21, and IGF-I was measured at 8 h. Mean salivary score increased with SF injection (P < .01; .4, 3.3, and 3.7 for 0, 30, and 60 micrograms of SF/kg BW, respectively), although there was a dose x day interaction (P < .01). Injection of SF reduced DMI (P < or = .01; 6.39, 4.95, and 2.64 kg of DM/d for 0, 30, and 60 micrograms of SF/kg BW, respectively). Mean ruminal pH was increased (P < .01); 6.03, 6.42, and 6.72 for 0, 30, and 60 micrograms of SF/kg BW, respectively). Steers administered 60 micrograms of SF/kg BW lost weight (P = .02; 15.1 and -20.3 kg for 0 and 60 micrograms of SF/kg BW, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)

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Section: Discussionmentioning

confidence: 99%

The effect of daily slaframine injection of salivary score, feed intake, ruminal pH, and circulating concentrations of somatotropin and insulin-like growth factor I1

Hibbard

et al. 1995

Journal of Animal Science

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“…Acute dose-response, experimentation with single or tandem (8-h intervals) dosages of SF, given 158 CANADIAN JOURNAL OF ANIMAL SC'EA'CE intramuscularly (20-40 pg kg-t BW), increased salivation 43-68% (Froetschel et al 1986), reticulo-omasal orifice opening time by 30-33% (Kelly et al 1991) and ruminal liquid outflow by 22-26% (Froetschel et al 1987;Jacques et al 1989) (Gaskins et al 1990) and ruminal pH, fluid dilution and cellulolytic bacteria numbers (Bird et al 1993 (Froetschel et al 1989). These researchers speculated that the frequent feeding regimen compromised the effects of SF in that experiment.…”

mentioning

confidence: 99%

“…12, and 24 h after feeding, are shown in Table 5 (Croom et al 1990(Croom et al , 1903, causes sustained increases in saliva (Froetschel et al 1986) and pancreatic fluid flow (Walker etal. 1994 (Froetschel et al 1986).…”

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confidence: 99%

Effects of abomasal slaframine infusion on ruminal digesta passage and digestion in steers

Froetschel¹,

Streeter²,

Amos³

et al. 1995

Can. J. Anim. Sci.

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Metabolic responses to protein supplementation and slaframine in goats and sheep fed roughage

Gaskins

Croom

Fernandez

et al. 1991

Small Ruminant Research

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Effects of protein supplementation and parasympathetic stimulation with slaframine on utilization of low quality roughage fed to goats and sheep

Cited by 14 publications

References 18 publications

The effect of daily slaframine injection of salivary score, feed intake, ruminal pH, and circulating concentrations of somatotropin and insulin-like growth factor I1

The effect of daily slaframine injection of salivary score, feed intake, ruminal pH, and circulating concentrations of somatotropin and insulin-like growth factor I1

Effects of abomasal slaframine infusion on ruminal digesta passage and digestion in steers

Metabolic responses to protein supplementation and slaframine in goats and sheep fed roughage

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