Effects of progressive increase in body weight on lung function in six groups of body mass index

Melo, Saulo Maia D'Ávila; Melo, Valdinaldo Aragão de; Filho, Raimundo Sotero de Menezes; Santos, Fábio Almeida

doi:10.1016/s0104-4230(11)70103-8

Cited by 7 publications

(16 citation statements)

References 22 publications

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“…Unlike the findings of this work for SaO 2 , in those of D'Ávila et al 14 , the observed changes were shown at BMI values ≥ 51 kg/m 2 (morbid obesity), although it should be noted that their recorded changes in SaO 2 were ~ 95%, that is, normal values at sea level and for Mexico City's altitude 27,28 . The authors' values for PaO 2 and SaO 2 showed a clear GE deterioration starting from a BMI > 30 kg/m 2 (obesity group), which is observed even before morbid obesity is reached, unlike the observations previously reported by D'Ávila et al 14 , and as it occurs in severe obesity 5,7,8,11 , according to other specialists, without being able to specify that in reality it starts occurring since obesity (as noted in this work), given that only groups with morbid obesity (BMI > 40 kg/m 2 ) were studied. This earlier presentation of deterioration in these arterial blood gas variables appears to be related not only to BMI increase, but also to altitude.…”

Section: Discussioncontrasting

confidence: 98%

“…The required sample was calculated based on the study by D'Ávila et al 14 . This study categorized the obesity groups according to BMI, and for the GE variable, arterial oxygen saturation (SaO 2 ) was used.…”

Section: Interventionmentioning

confidence: 99%

“…Due to this, studying independent groups according to BMI category or groups with already established obesity or morbid obesity is preferred. In their research, D'Ávila et al 14 reported the behavior of expiratory flows (forced vital capacity [FVC] and forced expiratory volume in one second [FEV 1 ] of simple spirometry test according to BMI categories (independent groups), and as part of GE, only partial saturation of oxygen (SpO 2 ) was obtained.…”

Section: Introductionmentioning

confidence: 99%

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Deterioration of gas exchange in subjects with an increase in body mass index at an altitude of 2,240 m above sea level

Santos-Martínez¹,

Gómez-López²,

Arias-Jiménez³

et al. 2021

ACME

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Section: Discussioncontrasting

confidence: 98%

Section: Interventionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Deterioration of gas exchange in subjects with an increase in body mass index at an altitude of 2,240 m above sea level

Santos-Martínez¹,

Gómez-López²,

Arias-Jiménez³

et al. 2021

ACME

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“…In the absence of diagnostic confirmation, non-erosive reflux disease (NERD) is usually suspected 12 , 16 , 17 . In such patients, diagnosis requires esophageal pH testing, esophageal biopsy and, in some cases, esophageal impedance-pH testing 5 , 21 . Currently, NERD is distinguished from erosive esophagitis by conventional white-light EGD and distinguished from functional heartburn by esophageal pH testing, with or without impedancemetry.…”

Section: Introductionmentioning

confidence: 99%

“…Anatomopathological analysis of esophageal biopsies may be used to confirm GERD microscopically 5 , 21 . Advances in EGD technology have made it possible to identify previously undetectable changes potentially associated with non-erosive disease.…”

Section: Introductionmentioning

confidence: 99%

Minimal endoscopic changes in non-erosive reflux disease

Ratin¹,

Orso²

2015

ABCD, arq. bras. cir. dig.

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BackgroundGastroesophageal reflux disease is an increasingly common condition worldwide causing a considerable economic impact. More than half the patients with clinical symptoms of reflux disease display no mucosal erosions on esophagogastroduodenoscopy, making it impossible to confirm the diagnosis without further investigations.AimTo evaluate the correlation between minimal endoscopic changes on white-light esophagogastroduodenoscopy (carditis, mucosal thickening and invisibility of vessels) and histologic changes observed in distal esophageal biopsies in a sample of patients with symptoms suggestive of reflux disease, and to verify the specificity of these symptoms for non-erosive reflux disease.MethodsRetrospective, cross-sectional study based on information retrieved from a digital database at a Brazilian hospital for the period March-October, 2012. The sample consisted of previously untreated, non-smoking subjects aged >18 years with symptoms suggestive of reflux disease but no esophageal erosions, submitted to esophagogastroduodenoscopy and distal esophageal biopsy.ResultsThe final sample included 23 subjects. The most frequently observed change was invisibility of vessels (n=21; 91.3%), followed by mucosal thickening (n=15; 65.2%) and carditis (n=5; 21.7%). The correlation coefficient between each variable and the anatomopathological diagnosis was 0.386 for body mass index, 0.479 for mucosal thickening, -0.116 for invisibility of vessels, 0.306 for carditis and 0.462 for hiatal hernia.ConclusionAll patients displayed minimal endoscopic changes on esophagogastroduodenoscopy, but only mucosal thickening revealed a moderately significant correlation with severity of esophagitis, although increased body mass index values and the presence of hiatal hernia were also associated.

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The Physical Factors Affecting on FVC, ERV, and MVV of Korean Adults in Their 20s

et al. 2013

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Abstract.[Purpose] The aim of this study was to research the physical factors affecting vital capacity (FVC, ERV, MVV) of adults in their 20s.[Methods] Ninety-seven healthy adults without neurological and muscular disorders participated in this study. The physical factors were defined by gender, body mass index (BMI), smoking history, and postures. A Spiropalm (A-M systems, Sequim, WA, USA) was used to measure respiratory function (FVC, ERV, and MVV). Multiple regressions were used to research the physical factors affecting vital capacity (FVC, ERV, and MVV).[Results] The important physical factors found to be significantly associated with FVC, ERV, and MVV were gender and weight (R 2 = 0.756), smoking history (R 2 =0.179), and gender (R 2 =0.427), respectively. [Conclusion] This study indicated that gender and weight are important physical factors for vital capacity in Korean adults in their 20s.

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Effects of progressive increase in body weight on lung function in six groups of body mass index

Cited by 7 publications

References 22 publications

Deterioration of gas exchange in subjects with an increase in body mass index at an altitude of 2,240 m above sea level

Deterioration of gas exchange in subjects with an increase in body mass index at an altitude of 2,240 m above sea level

Minimal endoscopic changes in non-erosive reflux disease

The Physical Factors Affecting on FVC, ERV, and MVV of Korean Adults in Their 20s

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