Two papers form the core scientific basis of the present doctoral dissertation: the optimization and uncertainty quantification studies of methanol and formaldehyde combustion (Olm et al. [1], 2017) and ethanol combustion (Olm et al. [2], 2016). The method of comparing combustion mechanisms by investigating their behavior for different types of simulations and across varying ranges of experimental conditions was first employed for hydrogen (Olm et al. [3], 2014) and syngas combustion mechanisms (Olm et al. [4], 2015). Although these articles do not deal explicitly with the subject of alcohol combustion, they mark important steps in the development of a framework for analyzing and comparing combustion mechanisms and therefore form an integral part of this dissertation. The developed methodology of comparing mechanisms is described in Section 3.1 and utilized in two case studies (Sections 3.3 and 3.4).The author of this dissertation made significant contributions to articles dealing with the optimizations of a hydrogen combustion mechanism (Varga et al. [5], 2015) and a joint hydrogen and syngas mechanism (Varga et al. [6], 2016). In addition to the above, the author contributed simulation results to an article dealing with the measurement of laminar burning velocities of aqueous ethanol (Hinton et al. [7], 2018, University of Oxford), for which he was granted co-authorship. Furthermore, two first-and two secondauthor conference papers dealing with the scientific work that later appeared in journal articles were published [8][9][10][11].