Effects of postoperative osteoporosis treatment on subsequent fracture and the 5-year survival rates after hemiarthroplasty for hip fracture

Cobden, Adem; Cobden, Serap Bulut; Çamurcu, Yalkın; Üçpunar, Hanifi; Duman, Serda; Sofu, Hakan

doi:10.1007/s11657-019-0657-3

Cited by 9 publications

(12 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In particular, patients with secondary OFs were higher than those with primary fracture, but the diagnosis rate of osteoporosis was 30.3% (27/89) and medication rate only 19.1% (17/89), indicating that when OFs occur, BMD examination and diagnosis are active for patients who have not previously been diagnosed with osteoporosis, but medication is not adequately used. Cobden et al[7] investigated 562 patients with osteoporotic hip fracture aged >65 years and reported that 460 (82%) of them underwent no osteoporosis treatment after hip fracture surgery. And also Kim et al[32] reported low osteoporosis treatment rates after hip fractures.…”

Section: Discussionmentioning

confidence: 99%

“…[56] The social burden of fractures will increase throughout the world as the population ages, so the prevention of primary and secondary OFs is essential. [789] Fortunately, OFs are preventable and their understanding of the epidemiology could help us focus efforts on the patients at greatest risk. In addition, it is very important to recognize the risk of secondary fractures that may occur after initial OFs.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical Characteristics of Primary and Secondary Osteoporotic Fractures: Data from Single Referral Center Emergency Department

Choi

Park

2019

J Bone Metab

View full text Add to dashboard Cite

Background: To investigate the characteristics of patients with osteoporotic fractures (OF) who visited the emergency room, we analyzed the frequency and distribution of primary and secondary OF. Methods: From March 2015 to April 2017, 406 patients with OF were assigned to wrist (W; n=132), spine (S; n=78), and hip (H; n=196) according to the site. All subjects were classified as having primary fracture or secondary fracture. Age, fracture site, the risk of future fracture using Fracture Risk Assessment Tool (FRAX) were compared. Results: The mean age at fracture site was significantly different among the 3 groups, groups W (66.57±10.03), S (73.50±9.07), and H (78.50±7.72). The most common site of OF were in the order of wrist, spine, and hip with the increase of age. The FRAX scores significantly increased (P<0.001) in the order of W (8.35±5.67), S (10.74± 6.99), and H (13.88±7.98) in total patient, and same in primary fracture group (W, 7.50± 4.18; S, 9.76±5.91; H, 11.93±6.61; P<0.001). The main site of prior fractures in secondary fracture was same lesion, which means that the prior fracture of secondary wrist fracture was wrist fracture such as spine for spine, hip for hip. Conclusions: We determined that as age increasing, the major sites of OF were different and FRAX scores increased. The most common site for secondary fracture was the same one. Hence, the risk of subsequent fracture in same site should be noted after patient suffered OF.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinical Characteristics of Primary and Secondary Osteoporotic Fractures: Data from Single Referral Center Emergency Department

Choi

Park

2019

J Bone Metab

View full text Add to dashboard Cite

show abstract

“…Cobden et al [ 19 ] described that 460 out of 562 (82%) patients with hip fracture treated with hemiarthroplasty did not receive anti-osteoporotic treatment and screening in the follow-up time after the fracture. In the same report, women made up the majority of the 102 patients treated, BPs being the most used agents.…”

Section: Adherence To Treatmentmentioning

confidence: 99%

“…In the analysis of 102 patients who underwent hemiarthroplasty after hip fracture, the mean survival rate was 30.2–30.7% for non-treated patients and 33.3% for treated patients, with a 5-year survival rate 16% for BP-treated patients compared to 5% for non-treated ones ( p = 0.002) [ 19 ].…”

Section: Mortalitymentioning

confidence: 99%

See 1 more Smart Citation

Adherence to Anti-Osteoporotic Treatment and Clinical Implications after Hip Fracture: A Systematic Review

Dobre

Niculescu

Petca

et al. 2021

JPM

View full text Add to dashboard Cite

The role of anti-osteoporotic treatment as part of the secondary prevention after hip fracture in terms of mortality and re-fracture risk has been studied, and the results are promising. Decreased treatment adherence and compliance is a problem that needs to be addressed by healthcare professionals. A systematic review of the literature was performed using the PubMed database with terms that included hip fracture, mortality, second fracture, and specific anti-osteoporotic treatment. We included 28 articles, 21 regarding mortality and 20 re-fracture rates in hip fracture patients. All studies showed lower mortality after hip fracture associated with anti-osteoporotic treatment, mostly bisphosphonate agents. The re-fracture risk is still debatable, since conflicting data were found. Although most of the studies showed notable effects on mortality and re-fracture rates associated with anti-osteoporotic treatment, we still need more data to validate the actual results.

show abstract

The current situation in the approach to osteoporosis in older adults in Turkey: areas in need of improvement with a model for other populations

et al. 2021

View full text Add to dashboard Cite

Purpose The total number of older adults in Turkey is striking, amounting to around 8 million, and this translates into considerably higher numbers of cases of osteoporosis (OP) and fractures in older adults. In this article, we outlined the current situation of OP in older adults in Turkey and investigated the differences between Turkey and a representative developed European country (Belgium), in terms of the screening, diagnosis, and treatment of OP. Our intention in this regard was to identify areas in need of improvement and subsequently to make a clear call for action to address these issues. Methods Herein, considering the steps related to the OP approach, we made a complete review of the studies conducted in Turkey and compared with the literature recommendations. Results There is a need for a national osteoporotic fracture registry; measures should be taken to improve the screening and treatment of OP in older males, such as educational activities; technicians involved in dual-energy X-ray absorptiometry (DXA) scanning should undergo routine periodic training; all DXA centers should identify center-specific least significant change values; all older adults should be considered for routine lateral dorsolumbar X-ray imaging for the screening of vertebral fractures while ordering DXA scans; the inclusion of vertebral fracture assessment (VFA) software in DXA assessments should be considered; screening using a fracture risk assessment tool (FRAX) algorithm that is specific to Turkey should be integrated; the fortification of foods with vitamin D is required; the high fracture risk by country-specific FRAX algorithm and the presence of falls/high fall risk should be integrated in reimbursement terms; and finally, more "fracture liaison services" should be established. ConclusionWe suggest that the practical consideration of our suggestions will provide considerable support to the efforts for combating with the adverse consequences of OP in society. This approach can be subsequently modeled for other populations to improve the management of OP globally. KeywordsOsteoporosis • Current situation • Turkey • Older • Improvement Abbreviations BMD Bone mineral density DXA Dual-energy X-ray absorptiometry eGFR Estimated glomerular filtration rate ESCEO Economic evaluation of osteoporosis and osteoarthritis * Gulistan Bahat

show abstract

Effects of postoperative osteoporosis treatment on subsequent fracture and the 5-year survival rates after hemiarthroplasty for hip fracture

Cited by 9 publications

References 30 publications

Clinical Characteristics of Primary and Secondary Osteoporotic Fractures: Data from Single Referral Center Emergency Department

Clinical Characteristics of Primary and Secondary Osteoporotic Fractures: Data from Single Referral Center Emergency Department

Adherence to Anti-Osteoporotic Treatment and Clinical Implications after Hip Fracture: A Systematic Review

The current situation in the approach to osteoporosis in older adults in Turkey: areas in need of improvement with a model for other populations

Contact Info

Product

Resources

About