Effects of plant extracts and derivatives on cardiac K
+
, Nav, and Ca
v
channels: a review
Insa Seck,
Samba Fama Ndoye,
Michelle Vanessa Kamga Kapchoup
et al.
Abstract:Natural products (NPs) are endless sources of compounds for fighting against several pathologies. Many dysfunctions, including cardiovascular disorders, such as cardiac arrhythmias have their modes of action regulation of the concentration of electrolytes inside and outside the cell targeting ion channels. Here, we highlight plant extracts and secondary metabolites' effects on the treatment of related cardiac pathologies on hERG, Nav, and Cav of cardiomyocytes. The natural product's pharmacology of expressed r… Show more
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