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Cited by 22 publications
(8 citation statements)
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“…The present study has shown that the local injection of phytohaemagglutinin in mice produces a number of striking changes, which are in contrast to the virtually negative results previously obtained in rats treated systemically with this substance (26). A considerable increase in weight was recorded in the regional Fig.…”
Section: Discussioncontrasting
confidence: 53%
See 1 more Smart Citation
“…The present study has shown that the local injection of phytohaemagglutinin in mice produces a number of striking changes, which are in contrast to the virtually negative results previously obtained in rats treated systemically with this substance (26). A considerable increase in weight was recorded in the regional Fig.…”
Section: Discussioncontrasting
confidence: 53%
“…However, cultivation of mouse lympho cytes in vitro has proved to be fraught with difficulties (23). As very little information is available on the effect of PHA on lymphoid tissues in vivo (26), an investigation was undertaken to study the changes in the regional lymphnodes of intact and thymectomized mice after local injection of this substance.…”
Section: Introductionmentioning
confidence: 99%
“…Both these phases are seen in normal and irradiated rats. Eleves et al [2] have reported that PHA had no effect on the leukocyte count in normal rats, but the dosage they administered was small. Papac [5] reported that in rats exposed to 800 r and injected 1-2 h later with PHA, the latter had no protective effect on the leukocyte count.…”
Section: Discussionmentioning
confidence: 99%
“…However, N orins and M ars hall (22) found that the intracardiac injection of 100-300 mg PHA (Wellcome) killed all of 12 mice, 3 rats and 8 guinea pigs injected. E lves, R oath and Israels (19) injected PHA-M intraperitoneally and subcutaneously into rats at weekly intervals. The rats were killed after 4 weeks and the spleens examined histologi cally, no abnormal changes being noted.…”
Section: Thymusmentioning
confidence: 99%