Effects of NGF and Photobiomodulation Therapy on Crush Nerve Injury and Fracture Healing: A Stereological and Histopathological Study in an Animal Model

Şen, Esengül; Özkan, Nilüfer; Önger, Mehmet Emin; Kaplan, Süleyman

doi:10.1177/19433875221138175

Cited by 1 publication

(1 citation statement)

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“…It is now well established that PBM enhances adenosine triphosphate (ATP) production and provokes a brief modulation of reactive oxygen species (ROS) [14,15]. The prevailing theory suggests that specific parameters of irradiation of light and/or infrared light stimulate cytochrome c oxidase (CcO), leading to increased ATP production [11].…”

Section: Introductionmentioning

confidence: 99%

Photobiomodulation Therapy in the Management of "Black Triangles" Due to the Absence of the Gingival Interdental Papilla

El Mobadder,

Nammour

2024

Cureus

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The absence of an interdental papilla, termed "black triangle," presents a challenge in aesthetic restorations. Photobiomodulation therapy (PBMT) is the non-thermal therapeutic use of light in order to positively modulate biological activity and has shown promise in tissue regeneration, wound healing, and inflammation reduction. This case report introduces a modified PBM protocol known as "hemolasertherapy" aimed at regenerating the gingival interdental papilla to fill the black triangle. In this case report, a 34-yearold female with an unaesthetic black triangle between the maxillary central incisors presented for treatment. Before surgical intervention, our suggested protocol was proposed and explained, detailing potential risks and outcomes. After proper scaling root planning, a suggested protocol with PBM was made. PBM application with a 635 nm wavelength diode laser at four points around the area between the two maxillary central incisors was made: coronal third and apical third of the papilla and mesial and distal of the papilla. Then, bleeding was provoked with a curette inside the sulcus between 11 and 21 (concerned area) by applying pressure on the junctional epithelium and the supracrestal connective tissue. After a few seconds, blood spontaneously filled the "black triangle" coronal to the interdental papilla and was left undisturbed. At this point, PBM was applied again on the same four points already described. The irradiation parameters during all PBM treatments were contact mode and continuous mode, 635 nm wavelength, spot size of 8 mm, power of 50 mW, irradiation time on each point of 50 seconds, and energy density of 4.976 J/cm 2 . After the intervention, the patient was prohibited from smoking, using mouthwash, drinking, and brushing for two hours. The exact same procedure was repeated five and 10 days after the first intervention. Follow-up was made for three months after the intervention. The assessment indicated a minor increase in the papilla height, which was not enough for a complete closure of the "black triangle." However, there was a reduction in the appearance of the black triangle. This case report suggests that PBM if used within our suggested protocol can increase the height of the gingival interdental papilla leading to a more pleasant aesthetic appearance. It is important to note that its effectiveness might be limited to specific conditions. In summary, the presented case report showcased a slight extension of the gingival interdental papilla. Further studies are essential to validate these observations.

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Section: Introductionmentioning

confidence: 99%