2020
DOI: 10.1002/jat.4045
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Abstract: Parabens (PBs) are compounds widely used in industry for food and personal care products as antimicrobials and preservatives. Their indiscriminate use has resulted in their detection in different ecosystems so that humans and other organisms are highly exposed. Methylparaben (MePB), compared with other PBs, is mostly detected in food, personal care and baby care products. PBs could be linked to the generation of hormonal disorders and fertility impairment since their recent classification as endocrine disrupto… Show more

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Cited by 7 publications
(2 citation statements)
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“…Preantral follicles exposed to BP tended to decrease oocyte maturation, decrease E 2 production, and increase steroidogenic gene expression, but these results were not statistically significant (J. H. Kim & Jee, 2020 ). While not affecting oocyte viability, another study suggests that MP exposure to porcine oocytes inhibited expansion of the cumulus oocyte complex and final maturation of the oocyte (Barajas‐Salinas et al, 2021 ). In contrast, exposure to MP and BP did not alter the levels of E 2 , P 4 , or the mRNA levels of steroidogenic factors in human cumulus cells collected from women undergoing a standardized IVF protocol (Herrera‐Cogco et al, 2020 ).…”
Section: Parabensmentioning
confidence: 99%
“…Preantral follicles exposed to BP tended to decrease oocyte maturation, decrease E 2 production, and increase steroidogenic gene expression, but these results were not statistically significant (J. H. Kim & Jee, 2020 ). While not affecting oocyte viability, another study suggests that MP exposure to porcine oocytes inhibited expansion of the cumulus oocyte complex and final maturation of the oocyte (Barajas‐Salinas et al, 2021 ). In contrast, exposure to MP and BP did not alter the levels of E 2 , P 4 , or the mRNA levels of steroidogenic factors in human cumulus cells collected from women undergoing a standardized IVF protocol (Herrera‐Cogco et al, 2020 ).…”
Section: Parabensmentioning
confidence: 99%
“…In the study performed by Vo et al ( 2010 ) in rats exposed to paraben abnormalities in uterus morphology and in ovarian histopathology, decreased length of the estrous cycle and serum estradiol levels was noticed. MP altered porcine oocyte morphology and caused a reduction in cumulus cell expression which resulted in decreased oocyte maturation (Barajas-Salinas et al 2020 ). On the other hand, no effect of BP exposure was observed in case of fecundity, fertility, and reproductive parameters in different generations of rats (F0, F1, or F2) (Hubbard et al 2000 ).…”
Section: Discussionmentioning
confidence: 99%