Effects of Methionine Deficiency on the B Lymphocyte and Immunoglobulins of Cecal Tonsil in Cobb Broilers

Zhu, Maoqun; Ruan, Tao; Zeng, Qian; Wu, Biao

doi:10.1590/1806-9061-2019-1059

Cited by 3 publications

(3 citation statements)

References 25 publications

(26 reference statements)

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“…Methionine also plays a role in both humeral and cellular immunity since methionine deficiency significantly affects antibody titre and decreases serum levels of IgG, IgA, and IgM. Furthermore, methionine deficiency decreases the relative percentage of CD3 + , CD3 + /CD8 + , and CD3 + /CD4 + T lymphocytes ( 64 ). Given the importance of T cell immunity in the defence against COVID-19, this aspect of methionine deficiency is essential in the prevention of, and reduction in the severity of infection.…”

Section: Physical Inactivity Malnutrition and Covid-19mentioning

confidence: 99%

Nutritional Impact and Its Potential Consequences on COVID-19 Severity

et al. 2021

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Background: During late 2019 a viral disease due to a novel coronavirus was reported in Wuhan, China, which rapidly developed into an exploding pandemic and poses a severe threat to human health all over the world. Until now (May 2021), there are insufficient treatment options for the management of this global disease and shortage of vaccines. Important aspects that help to defeat coronavirus infection seems to be having a healthy, strong, and resilient immune system. Nutrition and metabolic disorders, such as obesity and diabetes play a crucial role on the community health situation in general and especially during this new pandemic. There seems to be an enormous impact of lifestyle, metabolic disorders, and immune status on coronavirus disease 2019 (COVID-19) severity and recovery. For this reason, it is important to consider the impact of lifestyle and the consumption of well-defined healthy diets during the pandemic.Aims: In this review, we summarise recent findings on the effect of nutrition on COVID-19 susceptibility and disease severity and treatment. Understanding how specific dietary features might help to improve the public health strategies to reduce the rate and severity of COVID-19.

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Section: Physical Inactivity Malnutrition and Covid-19mentioning

confidence: 99%

Nutritional Impact and Its Potential Consequences on COVID-19 Severity

et al. 2021

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“…In addition to the higher LIV, the absolute values of EVC and SPL were also higher, demonstrating the faster development of birds that received increasing levels of digestible methionine+cystine. Development, v. 9, n. 8, e74985242, 2020 (CC BY 4.0) | ISSN 2525-3409 | DOI: http://dx.doi.org/10.33448/rsd-v9i8.5242 Another important result was the increasing linear response shown by SPL with the levels of digestible methionine+cystine, which may indicate improvement of the immune system, since the weight of this organ is related to immunity and this organ is responsible for the processing of antigens (Ag), production of immunoglobulins (IgM), and the deposition and maturation of T lymphocytes (Turletti et al, 2008), corroborating studies that demonstrate this beneficial activity of methionine in the immune system (Kalvandi et al, 2019;Zhu et al, 2019).…”

Section: Resultsmentioning

confidence: 68%

“…Among the essential nutrients directly influencing birds' performance is methionine, the noteworthy first limiting amino acid to these animals when corn-and soybean meal-based diets are supplied. Methionine also performs several functions in the organism of birds and affects the immune system, the deposition of protein, the lipid metabolism, and the energy metabolism (Zhu et al, 2019;Figueiredo Jr et al, 2020;Jankowski et al, 2020). Development, v. 9, n. 8, e74985242, 2020 (CC BY 4.0) | ISSN 2525-3409 | DOI: http://dx.doi.org/10.33448/rsd-v9i8.5242 4 Some other functions of methionine include the donation of methyl radicals, precursors of the biosynthesis of cysteine, which, bound to the pairs by a disulfide bond, forms cystine, which is why nutritional recommendations are expressed as methionine+cystine (Bin et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Digestible methionine+cystine levels for white-egg layers aged one to six weeks

Figueiredo

Guerra

Santana

et al. 2020

RSD

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The aim of this study was was to determine the nutritional requirements of digestible methionine+cystine (M+C) for white-egg layers aged one to six weeks. A completely randomized design with five methionine+cystine levels, six replicates, and 30 birds per experimental unit was adopted. Dietary treatments consisted of five diets supplemented with DL-Methionine with resulted in five levels of digestible methionine + cystine, 80% (0.516%), 90% (0.578%), 100% (0.640%), 110% (0.702%), and 120% (0.764%), based on Brazilian tables of nutritional requirements. Performance, serological blood, and histological data were evaluated. Feed intake, feed conversion, hepatic glycogen deposition, enzymatic activity of alanine aminotransferase and gamma-glutamyl transferase, and serum creatinine and albumin levels had showed a quadratic response to the levels of digestible M+C, with the respective requirements: 89.78% (0.575%), 114.33% (0.732%), 86.50% (0.554%), 100% (0.640%), 100.40% (0.643%), 104.30% (0.668%), and 111.88% (0.716%). Increasing levels of methionine+cystine elevated the relative liver weight and the deposition of hepatic glycogen, in addition to promote higher growth in pullets, with better body weight and body weight gain and feed conversion ratio. Our findings suggest that 0.732% digestible methionine+cystine is recommended, which corresponds to an intake of 151.20 mg/bird/d and a Met+Cys:Lys ratio 83%, for light pullets from one to six weeks.

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Immunomodulatory effects of chicken soups prepared with the native cage-free chickens and the commercial caged broilers

Cai

et al. 2022

Poultry Science

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Effects of Methionine Deficiency on the B Lymphocyte and Immunoglobulins of Cecal Tonsil in Cobb Broilers

Cited by 3 publications

References 25 publications

Nutritional Impact and Its Potential Consequences on COVID-19 Severity

Nutritional Impact and Its Potential Consequences on COVID-19 Severity

Digestible methionine+cystine levels for white-egg layers aged one to six weeks

Immunomodulatory effects of chicken soups prepared with the native cage-free chickens and the commercial caged broilers

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