Effects of limited access to a fat option on food intake and body composition in female rats

Bingeing, Self‐restriction, and Increased Body Weight in Rats With Limited Access to a Sweet‐fat Diet

“…Many of these models used rebound hyperphagia paradigms that generally consist of experimenter‐imposed limited food access (11,12,13). Like the results of the present study, previous studies have shown that bingeing on palatable food can be induced without food deprivation (7,8,9,14). This lack of food deprivation increases the clinical validity of animal models of binge eating associated with eating disorders such as bulimia, because bulimics typically continue to eat between binges but restrict themselves to healthier foods during this time (4).…”

“…This study presents a new animal model of weight and total caloric intake dysregulation in rats that binge on a sweet‐fat diet. Just as previous models using other diets and periods of limited access to sugar‐ or fat‐rich diets have done (6,7,8,16), this model of limited sweet‐fat access could facilitate further characterization of binge eating in relation to physiological and neurological changes. Access to sweet‐fat chow for 2 h per day produces a more pronounced increase in body weight compared with standard chow available ad libitum .…”

Bingeing, Self‐restriction, and Increased Body Weight in Rats With Limited Access to a Sweet‐fat Diet

“…Many of these models used rebound hyperphagia paradigms that generally consist of experimenter‐imposed limited food access (11,12,13). Like the results of the present study, previous studies have shown that bingeing on palatable food can be induced without food deprivation (7,8,9,14). This lack of food deprivation increases the clinical validity of animal models of binge eating associated with eating disorders such as bulimia, because bulimics typically continue to eat between binges but restrict themselves to healthier foods during this time (4).…”

“…This study presents a new animal model of weight and total caloric intake dysregulation in rats that binge on a sweet‐fat diet. Just as previous models using other diets and periods of limited access to sugar‐ or fat‐rich diets have done (6,7,8,16), this model of limited sweet‐fat access could facilitate further characterization of binge eating in relation to physiological and neurological changes. Access to sweet‐fat chow for 2 h per day produces a more pronounced increase in body weight compared with standard chow available ad libitum .…”

Binge Eating in Rats with Limited Access to Vegetable Shortening

“…Because female hormones can affect food intake, males generally have been used in an attempt to isolate the effects of the access schedule. However, similar effects have been observed in female rats of the same age and strain, as well as in 4-month-, 17-month-, and 31-month-old male F344BNF1/NIA rats (Dimitriou et al, 2000;Thomas et al, 2002).…”

Bingeing rats: A model of intermittent excessive behavior?

“…This protocol provides a relatively simple and inexpensive means of establishing IEB that can be maintained for extended periods of time. The phenomenon is robust and reliable, as we have demonstrated it in different strains and ages of rats (Thomas et al, 2002), as well as in males and females Dimitriou et al, 2000).…”

“…To induce binge-type eating, limited access to an optional source of dietary fat (hydrogenated vegetable shortening) is provided. Our research has shown that, as access to the shortening decreases, consumption of the shortening increases during the 2-h limited access period (Corwin, 2004;Corwin, Wojnicki, Fisher, Dimitriou, Rice and Young, 1998;Dimitriou, Rice, & Corwin, 2000;Thomas, Rice, Weinstock, & Corwin, 2002). When rats only have access to the shortening for 2 h three times a week, intake during the 2-h access period is very high, i.e.…”

Bingeing, Self‐restriction, and Increased Body Weight in Rats With Limited Access to a Sweet‐fat Diet

“…Many of these models used rebound hyperphagia paradigms that generally consist of experimenter‐imposed limited food access (11,12,13). Like the results of the present study, previous studies have shown that bingeing on palatable food can be induced without food deprivation (7,8,9,14). This lack of food deprivation increases the clinical validity of animal models of binge eating associated with eating disorders such as bulimia, because bulimics typically continue to eat between binges but restrict themselves to healthier foods during this time (4).…”

“…This study presents a new animal model of weight and total caloric intake dysregulation in rats that binge on a sweet‐fat diet. Just as previous models using other diets and periods of limited access to sugar‐ or fat‐rich diets have done (6,7,8,16), this model of limited sweet‐fat access could facilitate further characterization of binge eating in relation to physiological and neurological changes. Access to sweet‐fat chow for 2 h per day produces a more pronounced increase in body weight compared with standard chow available ad libitum .…”

Binge Eating in Rats with Limited Access to Vegetable Shortening

“…Because female hormones can affect food intake, males generally have been used in an attempt to isolate the effects of the access schedule. However, similar effects have been observed in female rats of the same age and strain, as well as in 4-month-, 17-month-, and 31-month-old male F344BNF1/NIA rats (Dimitriou et al, 2000;Thomas et al, 2002).…”

Bingeing rats: A model of intermittent excessive behavior?

“…This protocol provides a relatively simple and inexpensive means of establishing IEB that can be maintained for extended periods of time. The phenomenon is robust and reliable, as we have demonstrated it in different strains and ages of rats (Thomas et al, 2002), as well as in males and females Dimitriou et al, 2000).…”

“…To induce binge-type eating, limited access to an optional source of dietary fat (hydrogenated vegetable shortening) is provided. Our research has shown that, as access to the shortening decreases, consumption of the shortening increases during the 2-h limited access period (Corwin, 2004;Corwin, Wojnicki, Fisher, Dimitriou, Rice and Young, 1998;Dimitriou, Rice, & Corwin, 2000;Thomas, Rice, Weinstock, & Corwin, 2002). When rats only have access to the shortening for 2 h three times a week, intake during the 2-h access period is very high, i.e.…”

Bingeing, Self‐restriction, and Increased Body Weight in Rats With Limited Access to a Sweet‐fat Diet

“…Many of these models used rebound hyperphagia paradigms that generally consist of experimenter‐imposed limited food access (11,12,13). Like the results of the present study, previous studies have shown that bingeing on palatable food can be induced without food deprivation (7,8,9,14). This lack of food deprivation increases the clinical validity of animal models of binge eating associated with eating disorders such as bulimia, because bulimics typically continue to eat between binges but restrict themselves to healthier foods during this time (4).…”

“…This study presents a new animal model of weight and total caloric intake dysregulation in rats that binge on a sweet‐fat diet. Just as previous models using other diets and periods of limited access to sugar‐ or fat‐rich diets have done (6,7,8,16), this model of limited sweet‐fat access could facilitate further characterization of binge eating in relation to physiological and neurological changes. Access to sweet‐fat chow for 2 h per day produces a more pronounced increase in body weight compared with standard chow available ad libitum .…”

Binge Eating in Rats with Limited Access to Vegetable Shortening

“…Because female hormones can affect food intake, males generally have been used in an attempt to isolate the effects of the access schedule. However, similar effects have been observed in female rats of the same age and strain, as well as in 4-month-, 17-month-, and 31-month-old male F344BNF1/NIA rats (Dimitriou et al, 2000;Thomas et al, 2002).…”

Bingeing rats: A model of intermittent excessive behavior?

“…This protocol provides a relatively simple and inexpensive means of establishing IEB that can be maintained for extended periods of time. The phenomenon is robust and reliable, as we have demonstrated it in different strains and ages of rats (Thomas et al, 2002), as well as in males and females Dimitriou et al, 2000).…”

“…To induce binge-type eating, limited access to an optional source of dietary fat (hydrogenated vegetable shortening) is provided. Our research has shown that, as access to the shortening decreases, consumption of the shortening increases during the 2-h limited access period (Corwin, 2004;Corwin, Wojnicki, Fisher, Dimitriou, Rice and Young, 1998;Dimitriou, Rice, & Corwin, 2000;Thomas, Rice, Weinstock, & Corwin, 2002). When rats only have access to the shortening for 2 h three times a week, intake during the 2-h access period is very high, i.e.…”