PLoS ONE volume 9, issue 5, Pe98401 2014 DOI: 10.1371/journal.pone.0098401 View full text
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Julio Plaza-Diaz, Carolina Gomez-Llorente, Francisco Abadia-Molina, Maria Jose Saez-Lara, Laura Campaña-Martin, Sergio Muñoz-Quezada, Fernando Romero, Angel Gil, Luis Fontana

Abstract: We have previously described the safety and immunomodulatory effects of Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036 in healthy volunteers. The scope of this work was to evaluate the effects of these probiotic strains on the hepatic steatosis of obese rats. We used the Zucker rat as a genetic model of obesity. Zucker-Leprfa/fa rats received one of three probiotic strains, a mixture of L. paracasei CNCM I-4034 and B. breve CNCM I-4035, or a place…

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