Effects of hypothalamic dopamine on growth hormone‐releasing hormone‐induced growth hormone secretion and thyrotropin‐releasing hormone‐induced prolactin secretion in goats

Jin, Jin; Hashizume, Takumi

doi:10.1111/asj.12333

Cited by 6 publications

(3 citation statements)

References 43 publications

(117 reference statements)

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“…It was preassumed that a low dosage of dopamine was adequately effective to boost a higher growth. According to Jin and Hashizume (2014), dopamine is involved in growth hormone and prolactin regulation mechanism in goat. Dopamine restrained the somatostatin hormone in hypothalamus, thus the growth hormone releasing hormone (GHRH) was able to be stimulated to secrete growth hormone.…”

Section: Discussionmentioning

confidence: 99%

Reproductive and growth performances in female giant freshwater prawn following inhibition of gonadal maturation using dopamine and medroxyprogesterone hormone

Wijaya

Sudrajat

Imron³

2020

Jurnal Akuakultur Indonesia

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Reproductive and growth performances in female giant freshwater prawn following inhibition of gonadal maturation using dopamine and medroxyprogesterone hormonePerforma reproduksi dan pertumbuhan pascapenghambatan pematangan gonad udang galah betina secara hormonal menggunakan dopamin dan medroxyprogesteron ABSTRACT One of the main problem in giant river prawn (GFP) culture is early gonadal maturation in female resulting a reduced growth performance. This problem cause economic losses. When GFP at gonadal maturation, somatic growth will be inhibited because energy is used for reproduction. A factorial experimental design using two factors, namely dopamine and medroxyprogesterone, with each factor consist of three levels was applied. Three dopamine levels were 0, 10 -5 mol/shrimp, and 10 -10 mol/shrimp, while the medroxyprogesterone levels were 0, 75 mg/1.5 mL/bodyweight, and 150 mg/3 mL/bodyweight with a density 15 individual/tank. The utilization of dopamine and medroxyprogesterone in GFP (initial bodyweight : 11.27 ± 0.97 g) through injection at the third periopod was done three times at week 0, 2 nd , and 4 th with two weeks interval. The results showed that hormone inhibitor treatments affected both growth and reproductive performances in female GFP. The treated individuals showed a lower gonadal maturity indicator values and faster growth rate than control. Gonadal maturity, as shown by gonad histology, in all treatments were lower (previtelogenic and vitellogenic stages) than that in control which is in mature stage. Estradiol concentration premix dopamine 10 -10 mol/shrimp and medroxyprogesterone 150 mg/3 mL/ bodyweight treatments are lower than control. In conclusion, dopamine and medroxyprogesterone administration could suppres GSI and gonad development, and also increase growth rate. ABSTRAKKematangan gonad dini induk udang galah Macrobrachium rosenbergii betina dapat merugikan. Saat udang matang gonad, pertumbuhan somatik terhambat disebabkan energi untuk pertumbuhan akan digunakan untuk reproduksi. Penelitian ini bertujuan mengevaluasi penggunaan hormon dopamin dan medroxyprogesterone sebagai penghambat pematangan gonad. Penelitian ini menggunakan rancangan acak lengkap faktorial dengan dua perlakuan yaitu pemberian dopamin dan medroxyprogesterone. Dosis dopamin yang digunakan yaitu 0, 10 -5 mol/udang, dan 10 -10 mol/udang, sedangkan medroxyprogesterone dengan dosis 0, 75 mg/1,5 mL/bobot udang, dan 150 mg/3 mL/bobot udang dengan kepadatan 15 ekor/bak. Udang galah betina (bobot awal:11,27 ± 0,97 g) diberi perlakuan berupa dopamin dan medroxyprogesterone sebanyak tiga kali pada minggu ke-0, 2, dan 4 dengan interval waktu dua minggu sekali. Hasil penelitian ini menunjukan perlakuan dopamin dan medroxyprogesterone memiliki nilai indeks kematangan gonad (IKG) yang rendah dan laju pertumbuhan yang lebih cepat dibandingkan kontrol. Histologi gonad pada semua perlakuan berada pada tahap previtellogenic dan vitellogenic dibandingkan kontrol yang berada pada tahap mature. Konsentrasi estradiol pada perlakuan pre...

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Section: Discussionmentioning

confidence: 99%

Reproductive and growth performances in female giant freshwater prawn following inhibition of gonadal maturation using dopamine and medroxyprogesterone hormone

Wijaya

Sudrajat

Imron³

2020

Jurnal Akuakultur Indonesia

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“…[ 2 ] Prolactin secretion is stimulated by thyrotropin releasing a hormone (TRH) and inhibited by dopamine. [ 3 ] Moreover, extra-pituitary prolactin found in the cerebral cortex, amygdala, myometrium, lacrimal glands, thymus, immune cell, skin fibroblast, sweat gland, and spinal cord this extra-pituitary prolactin is not regulated by dopamine but through independent factors. [ 4 ]…”

Section: Introductionmentioning

confidence: 99%

Assessment of serum prolactin levels in acute myocardial infarction: The role of pharmacotherapy

Al-Kuraishy¹,

Al-Gareeb²,

Awad³

et al. 2016

Indian J Endocr Metab

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Background:Hyperprolactinemia may reflect neuroendocrine stress reaction against acute coronary syndromes.Aim:The aim of the present study was evaluation of the serum prolactin level in the acute myocardial infarction (MI) regarding the current pharmacotherapy in management of MI.Setting and Design:Cross-sectional clinical based study.Subjects and Methods:This cross-sectional clinical study involved all patients with acute MI in a coronary care unit, a total number of 44 patients (45% males and 55% females) with age ranged from 40 to 75 years. A full history for modifiable risk factors and current therapy with aspirin, clopidogrel and or metformin, all patients are nonsmokers. The anthropometric measurements; for estimations of body mass index (kg/m2), electrocardiography was obtained. Fasting blood samples were taken in the morning from all patients and the sera used for estimations of routine investigation and determination of ischemic cardiac biomarkers like cardiac troponin I (cTnI) and serum prolactin level.Results:This study shows a significant increase in the serum prolactin in acute MI as compared with the control. In acute MI serum cTnI elevation was correlated with serum prolactin increments. In metformin-treated group, there was a lowest prolactin serum level.Conclusions:Serum prolactin level increased in acute MI, and positively correlated with cardiac troponin level and reflects underlying cardiovascular complications.

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“…DOM is a DA D 2 receptor antagonist (Yen ) that does not cross the BBB (Laduron & Leysen ; Delitala et al ); therefore, the hormonal changes observed could be mediated through the pituitary and median eminence. The secretion of PRL is also stimulated by thyrotropin‐releasing hormone (TRH) (Yen ; Hashizume et al , , , ; Sawada et al ; Yaegashi et al ; Jin & Hashizume ). TRH acts directly on the pituitary lactotrophs to secrete PRL (Yen ).…”

Section: Introductionmentioning

confidence: 99%

Effects of extracerebral dopamine on salsolinol‐ or thyrotropin‐releasing hormone‐induced prolactin (PRL) secretion in goats

Yuki

Kato

Itou

et al. 2016

Animal Science Journal

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The aim of the present study was to clarify the effect of extracerebral dopamine (DA) on salsolinol (SAL)-induced prolactin (PRL) secretion in goats. An intravenous injection of SAL or thyrotropin-releasing hormone (TRH) was given to female goats before and after treatment with an extracerebral DA receptor antagonist, domperidone (DOM), and the PRL-releasing response to SAL was compared with that to TRH. DOM alone increased plasma PRL concentrations and the PRL-releasing response to DOM alone was greater than that to either SAL alone or TRH alone. The PRL-releasing response to DOM plus SAL was similar to that to DOM alone, and no additive effect of DOM and SAL on the secretion of PRL was observed. In contrast, the PRL-releasing response to DOM plus TRH was greater than that to either TRH alone or DOM alone and DOM synergistically increased TRH-induced PRL secretion. The present results demonstrate that the mechanism involved in PRL secretion by SAL differs from that by TRH, and suggest that the extracerebral DA might be associated in part with the modulation of SAL-induced PRL secretion in goats.

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Effects of hypothalamic dopamine on growth hormone‐releasing hormone‐induced growth hormone secretion and thyrotropin‐releasing hormone‐induced prolactin secretion in goats

Cited by 6 publications

References 43 publications

Reproductive and growth performances in female giant freshwater prawn following inhibition of gonadal maturation using dopamine and medroxyprogesterone hormone

Reproductive and growth performances in female giant freshwater prawn following inhibition of gonadal maturation using dopamine and medroxyprogesterone hormone

Assessment of serum prolactin levels in acute myocardial infarction: The role of pharmacotherapy

Effects of extracerebral dopamine on salsolinol‐ or thyrotropin‐releasing hormone‐induced prolactin (PRL) secretion in goats

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