Abstract:Halofantrine hydrochloride (halfan) was administered via oral route to matured female wistar rats weighing 180-200 g. The Wistar rats were randomly selected and divided into six groups of four rats each, making a total of twenty four rats and coded A1, A2, A3, B1, B2 and B3. Groups A3 and B3 were used as controls. Three consecutive doses of 1 mg/100 g halfan each were administered to group A1 at six hourly intervals while three doses of 2 mg/100 g halfan each were administered to group A2 at six hourly interva… Show more
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