Effects of green tea (<i>Camellia sinensis</i>) mouthwash containing 1% tannin on dental plaque and chronic gingivitis: a double‐blinded, randomized, controlled trial

Radafshar, Golpar; Ghotbizadeh, Mahshid; Saadat, Farshid; Mirfarhadi, Nastaran

doi:10.1111/jicd.12184

Cited by 30 publications

(32 citation statements)

References 34 publications

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“…Also, there can be an idiosyncratic reaction of oral mucosal desquamations and soreness after the use of CHX [55]. Mouthwashes containing herbal extracts were investigated to have less or even no staining effect [58,59]. Based upon the existing evidence, no significant differences in the effects on plaque or gingivitis were observed between herbal and CHX mouthwashes.…”

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confidence: 99%

Effects of Herbal Mouthwashes on Plaque and Inflammation Control for Patients with Gingivitis: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

Cai

Chen

Perera

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Objective. The aim of this study was to evaluate the overall effects of herbal mouthwashes as supplements to daily oral hygiene on plaque and inflammation control compared with placebos and chlorhexidine (CHX) mouthwashes in the treatment of gingivitis. Methods. PubMed, EMBASE, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, and grey literature databases were searched. Only randomised controlled trials (RCTs) comparing herbal mouthwashes with placebos or CHX in the daily oral hygiene of patient with gingivitis were included to compare the effect of different mouthwashes on plaque and inflammation control. Results. A total of 13 studies satisfied the eligibility criteria, and 11 studies were included in meta-analyses. Significant differences were observed in favour of herbal mouthwashes compared with placebos in both plaque- and inflammation-related indices (Quigley-Hein Plaque Index, QHPI: WMD = −0.61, 95% CI (−0.80, −0.42), P<0.001; Gingival Index, GI: −0.28 (−0.51, −0.06), P=0.01; Modified Gingival Index, MGI: −0.59 (−1.08, −0.11), P=0.02; Gingival Bleeding Index, GBI: −0.06 (−0.09, −0.04), P<0.001). No significant difference was found between herbal and CHX mouthwashes. Conclusions. Herbal mouthwashes have potential benefits in plaque and inflammation control as supplements to the daily oral hygiene of patients with gingivitis. Although no difference was observed between herbal and CHX mouthwashes in the selected studies, further high-quality RCTs are needed for more firm support before advising patients with gingivitis about whether they can use herbal mouthwashes to substitute for CHX mouthwashes or not (PROSPERO registration number: CRD42019122841).

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confidence: 99%

Effects of Herbal Mouthwashes on Plaque and Inflammation Control for Patients with Gingivitis: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

Cai

Chen

Perera

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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“…Unlike synthetic antiseptics, this plant extract was able to reduce fungal and bacterial biomass in vivo, despite the fact that it was neither fungicidal nor bactericidal in vitro [51][52][53]. This result suggests that SV extract could be able to preserve protective oral biofilm [41]. In Table 1, comparison of species-specific microbial load from baseline (D0) to D14 and from baseline to D28 confirmed a synergy between S. mutans and C. albicans previously described by Falsetta et al in 2014 [12].…”

Section: Discussionmentioning

confidence: 92%

“…Due to the chemical complexity of plant extracts, the exact role of major plant components or synergies between plant components still remains in question. However, several clinical studies demonstrated the efficacy of various herbal extracts to reduce plaque deposits and to improve oral conditions such as chronic gingivitis and post-operative dental surgery [39][40][41]44]. The review of literature revealed that vitamins and antioxidants of vegetal origin could interfere with inflammatory reaction, free radicals and endothelin in damaged periodontal tissues [17][18][19]48].…”

Section: Discussionmentioning

confidence: 99%

“…Main natural compounds described as antimicrobial compounds are essential oils (complex mix of terpenoids and phenylpropane derivatives (aromatic compounds)) and tannins (phenolic products that can precipitate proteins, such as escin) [37][38][39][40][41][42]. Some vegetal compounds display anti-inflammatory properties, such as vitamins, mineral elements (iron), proteases (papain and bromelain, a mix of acid proteases), or some flavonoids (close to tannins, such as baicalin) [41,[43][44][45][46]. Vitamins are essential organic substances that are required in small amounts to catalyze metabolic reactions [19].…”

Section: Introductionmentioning

confidence: 99%

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Solidago virgaurea L. Plant Extract Targeted against Candida albicans to Reduce Oral Microbial Biomass: A Double Blind Randomized Trial on Healthy Adults

et al. 2020

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Oral microbiome plays an important part on oral health and endogenous bacteria and fungi should not be eradicated. However, their proliferation must be controlled by oral hygiene care. In vitro, Solidago virgaurea ssp. virgaurea L. (SV) plant extract inhibits the adherence and hyphal formation of a fungus, Candida albicans. It reduces the biomass of Candida-bacterial biofilms but not fungal or bacterial growth. Unlike chemical antiseptics, like triclosan and chlorhexidine for instance, SV is a plant extract easily biodegradable. The purpose of this study was to assess the in vivo effectiveness of SV extract in reducing oral biomass. A randomized, double-blind clinical study, with dental plaque evaluation designed to assess the effectiveness of a fluorinated toothpaste containing SV (Bucovia™, Givaudan, Vernier, Switzerland) was conducted. Sixty-six subjects (SV group n = 33 vs. control n = 33) brushed their teeth twice a day for a 4-week period. Supragingival dental plaque was sampled. Total bacterial load (broad spectral bacterial quantitative Polymerase Chain Reaction (qPCR)), C. albicans and seven bacterial species were quantified by qPCR. In the Intervention group, there was a decrease of Total bacterial load (ΔD0D28 p = 0.005 and ΔD14D28 p = 0.026), Streptococcus mutans (ΔD0D14 p = 0.024) and C. albicans (ΔD0D28 p = 0.022). In the Control group Total bacterial load tended to decrease from baseline to day 28 (ΔD0D28 p = 0.062 and ΔD14D28 p = 0.009). Plaque Index and Gingival Index improved in both groups.

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“…This additional effect on biofilm removal could not be demonstrated with dental floss, wooden toothpicks, or oral irrigators . Obstacles to help explain the lack of clinical effectiveness of mechanical biofilm control for the majority of patients are numerous, and include limited time of use, lack of motivation, poor manual dexterity, tooth crowding, and tooth alignment …”

Section: Introductionmentioning

confidence: 99%

Novel natural product‐based oral topical rinses and toothpastes to prevent periodontal diseases

Laleman

Teughels

2020

Periodontology 2000

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There is increasing public interest in natural or herbal‐based healthcare products. This trend is not only visible in supermarkets and dental practices, but also in the scientific world. An improving number of clinical trials are being conducted to validate the claims made about these products in regards to periodontal health. Among single component preparations, Aloe vera and green tea are the most studied natural ingredients. Concerning polyherbal mixtures, triphala has garnered great interest. The effects of these natural products on periodontal health is encouraging, with almost all studies showing an inhibitory effect on plaque accumulation and an improvement in gingival health. However, more studies are needed to be able to design clinical guidelines to guide the use of these natural products in periodontal practice. For most of these products, few studies are available and, moreover, the available studies are limited in duration, the number of participants, and the specific composition of the natural product is often not described in detail.

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Effects of green tea (Camellia sinensis) mouthwash containing 1% tannin on dental plaque and chronic gingivitis: a double‐blinded, randomized, controlled trial

Abstract: The 1% tannin green tea mouthwash could be a safe and feasible adjunct to mechanical plaque control. The tested green tea mouthwash could be considered a good alternative for chlorhexidine in contraindicating situations.

Cited by 30 publications

References 34 publications

Effects of Herbal Mouthwashes on Plaque and Inflammation Control for Patients with Gingivitis: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

Effects of Herbal Mouthwashes on Plaque and Inflammation Control for Patients with Gingivitis: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

Solidago virgaurea L. Plant Extract Targeted against Candida albicans to Reduce Oral Microbial Biomass: A Double Blind Randomized Trial on Healthy Adults

Novel natural product‐based oral topical rinses and toothpastes to prevent periodontal diseases

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