Effects of flaxseed on rat milk creamatocrit and its contribution to offspring body growth

Abstract

Objectives: To assess the effect of flaxseed on rat milk creamatocrit and its contribution to offspring weight gain during lactation. Methods:The study was conducted with 22 Lister Hooded rats divided into two groups: Control Group (CG, n = 11), which received a casein-based diet with 17% protein, and Flaxseed Group (FG, n = 11), which received a 25% flaxseed diet supplemented with 14% casein, totaling 17% protein. Food consumption was controlled per individual cage and litter size. Maternal milk creamatocrit and offspring weight variation until weaning age were also evaluated. ResumoObjetivos: Avaliar o efeito da semente de linhaça no crematócrito do leite de ratas e crescimento corporal dos filhotes durante a lactação.Métodos: Utilizou-se 22 ratas Lister Hooded divididas em dois grupos: controle (GC, n = 11), que recebeu ração caseína com 17% de proteína; e linhaça (GL, n = 11), que recebeu ração com 25% de linhaça acrescida de 14% de caseína, totalizando 17% de proteína. Controlou-se o consumo de ração das ratas por gaiola individual, número de crias, e avaliou-se o crematócrito do leite materno e variação ponderal dos filhotes até idade de desmame.Resultados: O GL foi semelhante ao GC no consumo de ração das ratas (GL = 76,46±31,87 g; GC = 76,7±33,36 g; p = 0,9613) e equivalente ao GC no número de crias (GL = 4,94±2,34; GC = 5,5±3,19; p = 0,435). O mesmo foi verificado no teor de gordura do leite materno (GL = 18,4±4,76; GC = 15,3±6,03; p = 0,204) e valor energético total (GL = 212,92±46,4; GC = 181,1±60; p = 0,1964). O GL assemelhou-se ao GC tanto no peso corporal dos filhotes ao desmame (GL = 37±6,96 g; GC = 2,6±7,5 g; p = 0,1817) quanto na evolução ponderal (GL = 31,8±7,0 g; GC = 27,7±7,5 g; p = 0,2104).Conclusão: Um total de 25% de linhaça promoveu um crescimento adequado aos filhotes. J Pediatr (Rio J). 2012;88(1):74-8:Linhaça, caseína, rato, crematócrito, ômega-3, crescimento corporal. Effects of flaxseed on rat milk creamatocrit and its contribution to offspring body growth IntroduçãoDurante a gravidez, as necessidades maternas placentá-rias e fetais para os ácidos graxos poliinsaturados de cadeia longa (long chain polyunsaturated fatty acids) são elevadas. Sendo assim, uma dieta materna com aporte adequado desses lipídios durante o período gestacional e de lactação é de extrema importância, principalmente os da série ômega-3, em especial o ácido docosa-hexaenóico (DHA), já que a maior necessidade desse lipídio acontece durante a vida intraute-

Body adiposity and bone parameters of male rats from mothers fed diet containing flaxseed flour during lactation

“…Conversely, linoleic acid (LA, 18:2n-6) contributes to bone reabsorption and adipocyte hypertrophy. 7,8 In this context, the flaxseed (Linum usitatissimum) has been described as an excellent ALA source, presenting an average of 30% lipids in its composition, with 51-55% corresponding to ALA. 9,10 Furthermore, because of the presence of dietary fiber, high-quality proteins, antioxidants and minerals, a number of which offer synergistic health benefits and are part of basic nutrition, flaxseed is included in the following categories: functional foods and bioactive food. 11,12 In previous experimental models, our group evidenced protective effects of diet containing 25 out of 100 g flaxseed flour on glycemia, cardiovascular risk and lipid profile reduction.…”

Maternal Intake of Flaxseed During Lactation and Exercise Training Protect Against Salt Overload-Induced Aortic Remodeling in Adult Offspring

“…The present study showed that maternal intake of a flaxseed diet during lactation associated with exercise In a review study on the effects of flaxseed flour intake during pregnancy and lactation on the offspring's body mass at 21 days, 11 it was observed that the consumption of flaxseed flour in a concentration of 25% (25g flour/100g of feed) in the diet did not lead to changes in the animals' body mass at weaning, showing the same body mass as the animals of control rat dams. [21][22][23][24] In our study, although no statistically difference was found, a trend to lower body mass in animals of rat dams that consumed flaxseed diet during lactation was found. Other studies [25][26][27] reported lighter body mass of male offspring of rat dams who consumed flaxseed diet when compared to offspring of rat dams who consumed a control diet.…”

Relationship Between the Diet Quality Index in Nursing Mothers and the Fatty Acid Profile of Mature Breast Milk

“…Foods like oleaginous fruits, seeds, vegetables, egg yolk, octopus, and ruminant meat are also relevant sources of omega-3. 25 A study performed by Leite et al 26 in female rats showed that linseed is a good source of protein and lipids, providing adequate growth to the pups during lactation; however, they emphasized the importance of further studies to assess the transfer of omega-3 FA from this seed to breast milk.…”