1999
DOI: 10.1002/(sici)1099-1573(199903)13:2<106::aid-ptr362>3.0.co;2-2
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Effects of extracts of seed and leaf ofPiper guineense on skeletal muscle activity in rat and frog
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Cited by 25 publications
(10 citation statements)
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“…This may be as a result of the toxicity effect of the plant powder that might have arisen from the presence of constituents which are known to exhibit medicinal as well as physiological activities (Ismaila et al 201); some of the constituents are also known to provide a defensive mechanism against attack by insect pest which can impair physiological development of the various stages of insect pests and microorganism (Oluwalana, 2007). This bioactive agent could cause a depolarizing neuromuscular blocking action which could lead to the death of insect (Udoh et al, 1999). The phytochemical constituent discovered in this study is in tandem with the findings of Zabri et al 2008 andAbere andOnwukaeme, 2012.…”
Section: Discussion
supporting
confidence: 86%
“…This may be as a result of the toxicity effect of the plant powder that might have arisen from the presence of constituents which are known to exhibit medicinal as well as physiological activities (Ismaila et al 201); some of the constituents are also known to provide a defensive mechanism against attack by insect pest which can impair physiological development of the various stages of insect pests and microorganism (Oluwalana, 2007). This bioactive agent could cause a depolarizing neuromuscular blocking action which could lead to the death of insect (Udoh et al, 1999). The phytochemical constituent discovered in this study is in tandem with the findings of Zabri et al 2008 andAbere andOnwukaeme, 2012.…”
Section: Discussion
supporting
confidence: 86%
“…) implying that the mechanism(s) involved may not only be by increasing presynaptic inhibition in the spinal cord (Mycek et al, 1997). The muscle relaxant results obtained in this study corroborated earlier report in which methanolic extract of the plant demonstrated muscle relaxant effect in rat and frog in vitro (Udoh et al, 1999). The results may be used to justify the ethno-medicinal uses of the fruits of the plant particularly in the management of pain and arthritis among other uses.…”
Section: Table
supporting
confidence: 89%
“…Many health benefits, including the therapeutic values reported by people we investigated, have been described for clove (Heinrich and Barnes 2004;Jirovetz et al 2006;Chaieb et al 2007), and for black pepper and white pepper (Sofowora 1982;Achinewhu et al 1995;Noumi et al 1998;Udoh et al 1999;Mbongue et al 2005;Ahmad et al 2012). However, these spices can also be harmful to consumers in case of contamination by mycotoxins such as OTA.…”
Section: Discussion
mentioning
confidence: 71%
