Effects of exercise training with blood flow restriction on blood pressure in medicated hypertensive patients

Abstract

The development of non-pharmacological approaches to hypertension (HA) is critical for both prevention and treatment. This study examined the hemodynamic and biochemical responses of medicated hypertensive women to resistance exercise with blood flow restriction (vascular occlusion). Twenty-three women were randomly assigned to one of three groups: High intensity strength training (n = 8); low-intensity resistance exercise with occlusion (n = 8); and control (n = 7). The first two groups underwent eight weeks of training performed twice a week, including three series of wrist flexion exercises with or without vascular occlusion. The exercised with occlusion group showed pre-to post-test reduction in systolic and diastolic blood pressure, mean arterial pressure, and double product, whereas the other groups showed no significant hemodynamic changes. In conclusion, resistance exercise during 8 weeks was effective in lowering blood pressure in medicated hypertensive subjects.

Influence and reliability of lower-limb arterial occlusion pressure at different body positions

“…Within BFRE, higher pressures have been shown to cause greater CV responses to exercise ( Rossow et al, 2012 ) and may result in full restriction of arterial inflow to the working muscle. It has been speculated that this may increase the risk of ischemic reperfusion injury, peripheral nerve injury or concerning hemodynamic alterations ( Kacin et al, 2015 ; Loenneke et al, 2011 ; Jessee et al, 2016 ), particularly when BFRE is used in patients with blood-related conditions such as hypertension and heart disease ( Madarame et al, 2010 ; Cezar et al, 2016 ). Additionally, although the focus of this study was not on the physiological responses to BFR, higher pressures are known to increase discomfort responses to BFRE ( Jessee et al, 2017 ; Mattocks et al, 2017 ) and thus could impact upon the clinical utility of BFRE training and patient adherence to clinical rehabilitation programmes.…”

Effect of walk training combined with blood flow restriction on resting heart rate variability and resting blood pressure in middle-aged men

“…However, some studies have indicated that exercise with BFR exercise seems to be safe in hypertensive subjects because they did not present any adverse events [30][31][32] . Furthermore, the acute effect during exercise with BFR slightly increases SBP 30 , whereas the chronic effect decreases SBP in hypertensive subjects 31 . In relation to vascular diseases, there is not enough evidence to obtain consensus about the impact of training with BFR on vascular function.…”

Peer Review #1 of "Influence and reliability of lower-limb arterial occlusion pressure at different body positions (v0.1)"

“…Within BFRE, higher pressures have been shown to cause greater CV responses to exercise (Rossow et al, 2012) and may result in full restriction of arterial inflow to the working muscle. It has been speculated that this may increase the risk of ischemic reperfusion injury, peripheral nerve injury or concerning hemodynamic alterations (Kacin et al, 2015;Loenneke et al, 2011;Jessee et al, 2016), particularly when BFRE is used in patients with blood-related conditions such as hypertension and heart disease (Madarame et al, 2010;Cezar et al, 2016). Additionally, although the focus of this study was not on the physiological responses to BFR, higher pressures are known to increase discomfort responses to BFRE (Jessee et al, 2017;Mattocks et al, 2017) and thus could impact upon the clinical utility of BFRE training and patient adherence to clinical rehabilitation programmes.…”