Effects of epinephrine and vasopressin on median fibrillation frequency and defibrillation success in a porcine model of cardiopulmonary resuscitation

Median Frequencies of Prolonged Ventricular Fibrillation treated by V-A ECMO Correspond to a Return of Spontaneous Circulation Rate

“…A weak correlation between VF wave frequencies and CoPP was observed in our present study. In general, it is widely accepted that adequate CoPP is a key prerequisite for ROSC in prolonged CA (40,41). The correlation of the MF and CoPP corresponds to previously obtained data and supports the ability of the MF to reflect the overall coronary perfusion and resuscitability rate (5,11,42).…”

Median Frequencies of Prolonged Ventricular Fibrillation treated by V-A ECMO Correspond to a Return of Spontaneous Circulation Rate

“…A weak correlation between VF wave frequencies and CoPP was observed in our present study. In general, it is widely accepted that adequate CoPP is a key prerequisite for ROSC in prolonged CA (40,41). The correlation of the MF and CoPP corresponds to previously obtained data and supports the ability of the MF to reflect the overall coronary perfusion and resuscitability rate (5,11,42).…”

Endocardial activation during ventricular fibrillation in normal and failing canine hearts

“…Because centroid (or median) frequency avoids this problem, it has been promoted as a better descriptor for the dominant frequency components of the power spectrum in VF than peak frequency. Centroid frequency may be clinically useful, as it can help predict successful cardioversion in both animal models (6,47) and human patients (2,4,45,46). We found that centroid frequency, like peak frequency, did not change in CHF compared with normal dogs.…”

Systematic review of swine models for ventricular fibrillation induction in evaluating cardiopulmonary resuscitation methods

“…First, we were unable to stratify the types of CPR interventions due to the heterogeneity of CPR interventions (including defibrillation, anti-arrhythmic drugs, adrenergic drugs, and mechanical CPR). Efforts were made to provide specific information in each article in Supplementary Material B [40–256] to identify the type of VF induction used in the experiment of interest. Second, the quality of the included studies was not assessed.…”

Median Frequencies of Prolonged Ventricular Fibrillation treated by V-A ECMO Correspond to a Return of Spontaneous Circulation Rate

“…A weak correlation between VF wave frequencies and CoPP was observed in our present study. In general, it is widely accepted that adequate CoPP is a key prerequisite for ROSC in prolonged CA (40,41). The correlation of the MF and CoPP corresponds to previously obtained data and supports the ability of the MF to reflect the overall coronary perfusion and resuscitability rate (5,11,42).…”

Endocardial activation during ventricular fibrillation in normal and failing canine hearts

“…Because centroid (or median) frequency avoids this problem, it has been promoted as a better descriptor for the dominant frequency components of the power spectrum in VF than peak frequency. Centroid frequency may be clinically useful, as it can help predict successful cardioversion in both animal models (6,47) and human patients (2,4,45,46). We found that centroid frequency, like peak frequency, did not change in CHF compared with normal dogs.…”

Systematic review of swine models for ventricular fibrillation induction in evaluating cardiopulmonary resuscitation methods

“…First, we were unable to stratify the types of CPR interventions due to the heterogeneity of CPR interventions (including defibrillation, anti-arrhythmic drugs, adrenergic drugs, and mechanical CPR). Efforts were made to provide specific information in each article in Supplementary Material B [40–256] to identify the type of VF induction used in the experiment of interest. Second, the quality of the included studies was not assessed.…”

Median Frequencies of Prolonged Ventricular Fibrillation treated by V-A ECMO Correspond to a Return of Spontaneous Circulation Rate

“…A weak correlation between VF wave frequencies and CoPP was observed in our present study. In general, it is widely accepted that adequate CoPP is a key prerequisite for ROSC in prolonged CA (40,41). The correlation of the MF and CoPP corresponds to previously obtained data and supports the ability of the MF to reflect the overall coronary perfusion and resuscitability rate (5,11,42).…”

Endocardial activation during ventricular fibrillation in normal and failing canine hearts

“…Because centroid (or median) frequency avoids this problem, it has been promoted as a better descriptor for the dominant frequency components of the power spectrum in VF than peak frequency. Centroid frequency may be clinically useful, as it can help predict successful cardioversion in both animal models (6,47) and human patients (2,4,45,46). We found that centroid frequency, like peak frequency, did not change in CHF compared with normal dogs.…”

Systematic review of swine models for ventricular fibrillation induction in evaluating cardiopulmonary resuscitation methods

“…First, we were unable to stratify the types of CPR interventions due to the heterogeneity of CPR interventions (including defibrillation, anti-arrhythmic drugs, adrenergic drugs, and mechanical CPR). Efforts were made to provide specific information in each article in Supplementary Material B [40–256] to identify the type of VF induction used in the experiment of interest. Second, the quality of the included studies was not assessed.…”