Effects of dietary iron and folate supplementation on the physiological changes produced in weanling rats by sodium saccharin exposure

Urothelial Cytotoxicity and Regeneration Induced by Dimethylarsinic Acid in Rats

“…The kidneys were also embedded in paraffin, stained with H&E and examined histopathologically. The BrdU labeling index was determined by immunohistochemistry, using anti-BrdU (Chemicon International, Temecula, CA) at a dilution of 1:50 and methodology previously described from our laboratory (Garland et al, 1993).…”

Urothelial Cytotoxicity and Regeneration Induced by Dimethylarsinic Acid in Rats

“…The kidneys were also embedded in paraffin, stained with H&E and examined histopathologically. The BrdU labeling index was determined by immunohistochemistry, using anti-BrdU (Chemicon International, Temecula, CA) at a dilution of 1:50 and methodology previously described from our laboratory (Garland et al, 1993).…”

Effect of Sulfosulfuron on the Urine and Urothelium of Male Rats

“…Histopathological diagnosis of the tissue was performed based on criteria described in Cohen ( 5) and Cohen et al (10). The labeling index in the bladder tissue was determined by immunohistochemical detection of BrdU (15).…”

Evaluation of Cell Proliferation in Rat Mammary Glands Is Not Predictive of the Carcinogenic Potential of Insulin In Vivo

“…This was performed with the observer blinded group identity on a minimum of 1 tissue section/animal/marker, the counting procedure was based on the procedure described elsewhere. 19 Where possible, sufficient random fields on one section of each mammary gland were examined to allow the assessment of 1,000 mammary gland epithelial cells. Cell nuclei demonstrating specific immunohistochemistry staining were counted as positive.…”

Urothelial Cytotoxicity and Regeneration Induced by Dimethylarsinic Acid in Rats

“…The kidneys were also embedded in paraffin, stained with H&E and examined histopathologically. The BrdU labeling index was determined by immunohistochemistry, using anti-BrdU (Chemicon International, Temecula, CA) at a dilution of 1:50 and methodology previously described from our laboratory (Garland et al, 1993).…”

Effect of Sulfosulfuron on the Urine and Urothelium of Male Rats

“…Histopathological diagnosis of the tissue was performed based on criteria described in Cohen ( 5) and Cohen et al (10). The labeling index in the bladder tissue was determined by immunohistochemical detection of BrdU (15).…”

Evaluation of Cell Proliferation in Rat Mammary Glands Is Not Predictive of the Carcinogenic Potential of Insulin In Vivo

“…This was performed with the observer blinded group identity on a minimum of 1 tissue section/animal/marker, the counting procedure was based on the procedure described elsewhere. 19 Where possible, sufficient random fields on one section of each mammary gland were examined to allow the assessment of 1,000 mammary gland epithelial cells. Cell nuclei demonstrating specific immunohistochemistry staining were counted as positive.…”

Urothelial Cytotoxicity and Regeneration Induced by Dimethylarsinic Acid in Rats

“…The kidneys were also embedded in paraffin, stained with H&E and examined histopathologically. The BrdU labeling index was determined by immunohistochemistry, using anti-BrdU (Chemicon International, Temecula, CA) at a dilution of 1:50 and methodology previously described from our laboratory (Garland et al, 1993).…”

Effect of Sulfosulfuron on the Urine and Urothelium of Male Rats

“…Histopathological diagnosis of the tissue was performed based on criteria described in Cohen ( 5) and Cohen et al (10). The labeling index in the bladder tissue was determined by immunohistochemical detection of BrdU (15).…”

Evaluation of Cell Proliferation in Rat Mammary Glands Is Not Predictive of the Carcinogenic Potential of Insulin In Vivo

“…This was performed with the observer blinded group identity on a minimum of 1 tissue section/animal/marker, the counting procedure was based on the procedure described elsewhere. 19 Where possible, sufficient random fields on one section of each mammary gland were examined to allow the assessment of 1,000 mammary gland epithelial cells. Cell nuclei demonstrating specific immunohistochemistry staining were counted as positive.…”