Brain and Behavior volume 2, issue 3, P211-220 2012 DOI: 10.1002/brb3.45 View full text
Jamie D. Feusner, Sarah Madsen, Teena D. Moody, Cara Bohon, Emily Hembacher, Susan Y. Bookheimer, Alexander Bystritsky

Abstract: Cranial electrotherapy stimulation (CES) is a U.S. Food and Drug Administration (FDA)-approved treatment for insomnia, depression, and anxiety consisting of pulsed, low-intensity current applied to the earlobes or scalp. Despite empirical evidence of clinical efficacy, its mechanism of action is largely unknown. The goal was to characterize the acute effects of CES on resting state brain activity. Our primary hypothesis was that CES would result in deactivation in cortical and subcortical regions. Eleven healt…

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