Effects of Continuous-Wave (670-nm) Red Light on Wound Healing

Erdle, Brandon; Brouxhon, Sabine M.; Kaplan, Martin M.; VanBuskirk, JoAnne; Pentland, Alice P.

doi:10.1097/00042728-200803000-00006

Cited by 15 publications

(23 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…13 Treated mice received two irradiations per day at 8 mW/cm 2 fluence for 312 sec per session, resulting in a total dose density of 2.5 J/cm 2 per session (5 J/cm 2 per day). This regimen is in general agreement with the one used by Erdle et al 14 Erdle et al used the same red light source and mouse strain (SKH-1), measured incisional wound healing, and demonstrated the high efficiency of chronic daily treatment at a dose of 3.6 J/cm 2 (either 450 sec at 8 mW/cm 2 or 37 min at 1.6 mW/cm 2 ).…”

Section: Evidence Supporting the Safety Of Red Lightsupporting

confidence: 84%

See 1 more Smart Citation

A Preliminary Study of the Safety of Red Light Phototherapy of Tissues Harboring Cancer

Myakishev-Rempel

Stadler

Brondon

et al. 2012

Photomedicine and Laser Surgery

View full text Add to dashboard Cite

show abstract

Section: Evidence Supporting the Safety Of Red Lightsupporting

confidence: 84%

“…We selected the red light dose and fluence very conservatively based on prior work from our laboratory. 13 The chosen regime is in general agreement with the one used by Erdle et al 14…”

supporting

confidence: 70%

A Preliminary Study of the Safety of Red Light Phototherapy of Tissues Harboring Cancer

Myakishev-Rempel

Stadler

Brondon

et al. 2012

Photomedicine and Laser Surgery

View full text Add to dashboard Cite

show abstract

“…Furthermore, in comparing the last session to the initial session, all participants in group B showed a reduction in pressure ulcer area, unlike the participants in group A, who showed an increase in pressure ulcer area (Figure 2). Similar results have been observed in other studies (Caetano et al, 2009;Erdle et al, 2008;Minatel et al, 2009;Whelan et al, 2003;).…”

Section: Discussionsupporting

confidence: 92%

Evaluation of healing of pressure ulcers through thermography: a preliminary study

et al. 2015

View full text Add to dashboard Cite

Introduction: Thermography is a surface thermal radiation measurement technique whose application has been expanding in the healthcare field. The unhealed wound is a serious public health problem because it intervenes in the quality of life of patients and may cause emotional and psychological losses. The wound temperature can provide quantitative data that allow for the healing process to be monitored. The aim of this study was to verify whether thermography can be used as a method to evaluate the healing of pressure ulcers. Methods: Eight participants with sacral pressure ulcers were recruited and randomly divided into two groups: A (control) and B (experimental). Both groups received standard treatment for a period of four weeks, which consisted of a daily cleaning of the pressure ulcers with physiological saline (sodium chloride 0.9%) followed by an alginate hydrogel dressing. The group B received light-emitting diode (LED) phototherapy in addition to standard treatment, three times a week, yielding a total of 12 sessions. Photographs and thermograms of each pressure ulcer were obtained in all sessions in both groups. Results: Pressure ulcers treated with LED phototherapy were healed. The pressure ulcer area of group B decreased over the 12 treatment sessions, whereas the pressure ulcer area of group A increased. The ulcer temperature of group B was higher than that of group A during the treatment (temperature difference up to 7.6%). Discussion: The present study suggests a relationship between the temperature and area of pressure ulcers and proposes thermography as an adjunctive method for the evaluation of healing processes.

show abstract

“…Outro estudo que avaliou o efeito de um LED sobre a reparação tecidual foi o de Erdle et al (2008). Neste estudo foi demonstrado que uma luz vermelha com comprimento de onda de 670nm emitida por um LED, pode acelerar a reparação tecidual em incisões realizadas em ratos e também, apesar de não tão efetivamente, em feridas causadas por queimadura.…”

Section: Laser Em Baixa Intensidade Na Reparação Tecidualunclassified

“…Neste estudo foi demonstrado que uma luz vermelha com comprimento de onda de 670nm emitida por um LED, pode acelerar a reparação tecidual em incisões realizadas em ratos e também, apesar de não tão efetivamente, em feridas causadas por queimadura. Os autores ainda concluem que esta pode ser uma tecnologia bastante útil e que estudos em humanos, além daqueles existentes na área de mucosite, devem ser levados adiante (ERDLE, 2008).…”

Section: Laser Em Baixa Intensidade Na Reparação Tecidualunclassified

Avaliação da reparação tecidual de excisões realizadas em dorso de ratos submetidas à terapia foto-dinâmica com utilização de corante azul de metileno

Sperandio¹

View full text Add to dashboard Cite

The photodynamic therapy involves delivering visible light of the appropriate wavelength into a tissue or microorganism previously exposed to a photo-sensitive dye. Its use is widely spread between neoplastic and infeccious diseases. Nevertheless, its effects upon wound healing has not yet been completely verified and the few studies concerning this subject present whether good or bad results. In addition, studies that involve low intensity laser therapy or photodynamic therapy on wound healing concern mostly on the organization and quantification of the extracellular matrix components. Studying the epithelium, on the other hand, by the keratinocyte expressed proteins is equally important, once the wound healing depends also of the organization and proliferation of the epithelial cells. This study evaluated the wound healing of excisions performed on the back of rats submitted to low intensity laser therapy or photodynamic therapy mediated by methylene blue dye. Morphological and histo-morphological analysis of the wounds in predetermined periods were performed, as well as immunohistochemistry of citokeratins 10 and 14 and p63. The results showed that the wound healing was enhanced by the low intensity laser therapy, which was confirmed by the morphological and histomorphological analysis. The wound closure was previously seen for the laser group. The citokeratin 10 expression on the epithelial tongue of the wounds that belong to the laser group preceded the expression in the other groups, which indicated an accelerated maturation of this epithelium. The photodynamic therapy group did not present accelerated wound healing but did not present any delay as well. This suggests that the wound healing found for the laser group differs from that found for the photodynamic therapy group. Moreover, the lack of delay presented by the photodynamic therapy suggests a safe therapy with advantages regarding disinfection that should be considered in specific situations.

show abstract

Effects of Continuous-Wave (670-nm) Red Light on Wound Healing

Cited by 15 publications

References 22 publications

A Preliminary Study of the Safety of Red Light Phototherapy of Tissues Harboring Cancer

A Preliminary Study of the Safety of Red Light Phototherapy of Tissues Harboring Cancer

Evaluation of healing of pressure ulcers through thermography: a preliminary study

Avaliação da reparação tecidual de excisões realizadas em dorso de ratos submetidas à terapia foto-dinâmica com utilização de corante azul de metileno

Contact Info

Product

Resources

About