2021
DOI: 10.1016/j.ecoenv.2021.112968
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Effects of camptothecin on histological structures and gene expression profiles of fat bodies in Spodoptera frugiperda

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Cited by 7 publications
(2 citation statements)
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“…However, after feeding with leaves treated with CPT, the weight of the S. exigua larvae decreased compared to that treated with CPT alone, although there was no significant difference (p > 0.05) (Figure 6). These observations are consistent with previous findings in other insects, including Spodoptera frugiperda [29,30]. CPT diets induced weight loss of the larvae of S. frugiperda and the molecular basis for the impact of CPT on S. frugiperda was explored by comparative transcriptomic analyses among midgut samples.…”
Section: Rnai Targeting Segrx1 Increased the Sensitivity Of Cpt Again...supporting
confidence: 90%
“…However, after feeding with leaves treated with CPT, the weight of the S. exigua larvae decreased compared to that treated with CPT alone, although there was no significant difference (p > 0.05) (Figure 6). These observations are consistent with previous findings in other insects, including Spodoptera frugiperda [29,30]. CPT diets induced weight loss of the larvae of S. frugiperda and the molecular basis for the impact of CPT on S. frugiperda was explored by comparative transcriptomic analyses among midgut samples.…”
Section: Rnai Targeting Segrx1 Increased the Sensitivity Of Cpt Again...supporting
confidence: 90%
“…exigua increased when glutaredoxin 1 was silenced by RNA interference . Most recently, CPT was also observed to affect the ultrastructure of the midgut and fat body in lepidopteran insects, and various genes with different functions were upregulated by treatment with CPT, including those encoding group II insect chitinase (chitinase 10) and group h chitinase (chitinase A). This result caught our attention because we previously reported 10-hydroxycamptothecin (10-HCPT) to be an inhibitor of chitinolytic enzymes from the Asian corn borer Ostrinia furnacalis …”
Section: Introductionmentioning
confidence: 99%