Effects of buspirone on influenza a virus infection in stressed mice

Freire‐Garabal, Manuel; Núñez, M. R.; Losada, C.; Pereiro, D.; Castro-Bolano, C.; Gândara, José Manoel Gonçalves; Varela-Patiño, M.P.; Rey-Méndez, Manuel

doi:10.1016/0024-3205(94)00505-m

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Buspirone In Ibd1

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2016

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“…220 Although high doses of buspirone potentially lower immune responses, lower dosages enhance the natural killer cell activation and improve the course of viral infections in mice subjected to chronic auditory stress. 221,222 These effects in stress-induced immunomodulation may in part be due to an interaction between norepinephrine, which inhibits lymphocyte proliferation in vitro, and activation of 5-HT1A receptors, which blunt this effect. 223 Buspirone and gastrointestinal function.…”

Section: Buspirone In Ibdmentioning

confidence: 99%

Empirically Supported Use of Psychiatric Medications in Adolescents and Adults with IBD

Thorkelson

Bielefeldt

Szigethy

2016

Inflammatory Bowel Diseases

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Antidepressant medications are frequently prescribed for depression, anxiety disorders, and chronic pain syndromes, but overall support for their efficacy is modest at best. Psychological interventions have growing support for having much more robust effects without the side effects of antidepressants and should be considered first-line treatment or at least an adjunct to psychotropic medications for these conditions.

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