1997
DOI: 10.1002/(sici)1098-2825(1997)11:3<158::aid-jcla7>3.0.co;2-6
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Effects of benidipine hydrochloride on antioxidant enzyme activity in stroke-prone spontaneous hypertensive rats (SHR-SP)
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Cited by 10 publications
(4 citation statements)
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“…Previous studies have mentioned the possible effects of electromagnetic fields and microwaves on the beating of isolated animal hearts (10,26,43). Our earlier studies on BIOCERAMIC showed that BIOCERAMIC promotes microcirculation and other effects by up-regulating calcium-dependent nitric oxide and calmodulin in different cell lines (33)(34)(35)39).…”
Section: Discussionmentioning
confidence: 99%
“…Previous studies have mentioned the possible effects of electromagnetic fields and microwaves on the beating of isolated animal hearts (10,26,43). Our earlier studies on BIOCERAMIC showed that BIOCERAMIC promotes microcirculation and other effects by up-regulating calcium-dependent nitric oxide and calmodulin in different cell lines (33)(34)(35)39).…”
Section: Discussionmentioning
confidence: 99%
“…However, prior investigations have demonstrated that BIOCERAMIC promotes nitric oxide enhancement through calcium-dependent nitric oxide synthetase (35,36). BIOCERAMIC may also have effects on calcium ion movement, and therefore, influence central nervous system regulation of the cardiovascular system and the endocrine system, thereby changing stress-induced cardiovascular hemodynamic parameters (5,43,49).…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, based on the results of in vitro 38 and in vivo experiments, 39 benidipine appears to inhibit apoptosis in patients with renal dysfunction to preserve renal function. Although the mechanism by which benidipine inhibits apoptosis is not clear, the anti‐oxidant effect of benidipine is likely to be related because free radicals induce apoptosis of cells 40 and benidipine has an anti‐oxidant effect 41,42 …”
Section: Discussionmentioning
confidence: 99%
“…It has been reported that benidipine increases NO release in the heart via unknown mechanisms (19,20). However, the reported antioxidant activities of benidipine may explain its effect on NO release (21,22).…”
Section: Discussionmentioning
confidence: 99%
