Effects of antioxidant vitamins A, C, E and trace elements Cu, Se on CuZn SOD, GSH-Px, CAT and LPO levels in chicken erythrocytes

Abstract

The biologically damaging effects of reactive oxygen species are controlled in vivo by a wide spectrum of antioxidant defence mechanisms. Dietary constituents of antioxidant vitamins and trace elements may play an important role in protecting against oxidant damage. The effects of supplementation of vitamins A, C, E and trace elements Cu and Se on the activities of antioxidant enzymes and lipid peroxide levels in chicken erythrocytes were investigated depend on the time. CuZnSOD activity and plasma Cu levels in the Cu group were increased by 39 and 37 per cent respectively. CuZnSOD activity in vitamin C groups was also increased by 20 per cent. The GSH-Px activity in Se, Se+E and Se+Cu groups was raised by 35, 46 and 69 per cent respectively. Also, the GSH-Px activity in the vitamin C group was increased by 33 per cent. Catalase activity in all of these groups was not significantly different when compared with controls (p<0.01). The maximum decrease in LPO levels of 42 per cent was obtained for the Se+E group.

Effect of packing on changes in erythrocyte osmotic fragility and malondialdehyde concentration in donkeys administered with ascorbic acid

“…The result of MDA concentration obtained in the present study shows that EOF may be of better value in the determination of post-packing stress than MDA concentration, and may be a better biomarker of oxidative stress in donkeys subjected to packing. The finding of the present study also disagreed with the result of Aydemir et al (2000) that AA strongly reduces MDA concentration in erythrocytes of chickens.…”

Effects of stress produced by adrenocorticotropin (ACTH) on lipid peroxidation and some antioxidants in vitamin C treated and nontreated chickens

“…In this study, the GSH-Px activity increased in the control and vitamin C treated groups after ACTH application, but the increase was not statistically significant. Some reports indicated that the rise in GSH-Px activity may be a response to the need for further enzymatic capacity to deal with the production of H 2 O 2 possibly associated with increased SOD activity and plasma vitamin C level (Aydemir et al, 2000;Öztürk-Ürek et al, 2001).…”

Antioxidation status and histidine dipeptides content in broiler blood and muscles depending on protein sources in feed

“…Supplementation with antioxidative vitamins (A, C, E) and mineral micronutrients (including Cu and Se) increased the SOD activity, but did not affect the catalase activity in chicken blood and enhanced glutathione peroxidase GPx in brain tissue (Aydemir et al, 2000). In our studies, the used diets significantly affected only selected antioxidant blood parameters.…”