Effects of agricultural pesticides on the immune system of Xenopus laevis and Rana pipiens

Christin, Marie-Soleil; Ménard, Lucie; Gendron, Andrée D.; Ruby, Sylvia M.; Cyr, Daniel G.; Marcogliese, David J.; Rollins‐Smith, Louise A.; Fournier, Michel

doi:10.1016/j.aquatox.2003.11.007

Cited by 154 publications

(100 citation statements)

References 31 publications

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“…Christin et al (2004) exposed frogs (Xenopus laevis and Rana pipiens) to a mixture of herbicides and insecticides and found that at environmentally relevant concentrations, combinations of these pesticides altered aspects of the immune system. However, Davidson et al (2007) found no correlation between a common insecticide, carbaryl, and amphibians' susceptibility to the amphibian chytrid fungus (Batrachochytrium dendrobatidis, Bd).…”

Section: Introductionmentioning

confidence: 99%

Pesticide concentrations in frog tissue and wetland habitats in a landscape dominated by agriculture

Smalling

Reeves

Muths

et al. 2015

Science of The Total Environment

124

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Habitat loss and exposure to pesticides are likely primary factors contributing to amphibian decline in agricultural landscapes. Conservation efforts have attempted to restore wetlands lost through landscape modifications to reduce contaminant loads in surface waters and providing quality habitat to wildlife. The benefits of this increased wetland area, perhaps especially for amphibians, may be negated if habitat quality is insufficient to support persistent populations. We examined the presence of pesticides and nutrients in water and sediment as indicators of habitat quality and assessed the bioaccumulation of pesticides in the tissue of twonative amphibian species Pseudacris maculata (chorus frogs) and Lithobates pipiens (leopard frogs) at six wetlands (3 restored and 3 reference) in Iowa, USA. Restored wetlands are positioned on the landscape to receive subsurface tile drainage water while referencewetlands receive water fromoverland run-off and shallow groundwater sources. Concentrations of the pesticides frequently detected inwater and sediment samples were not different between wetland types. The median concentration of atrazine in surface water was 0.2 μg/ L. Reproductive abnormalities in leopard frogs have been observed in other studies at these concentrations. Nutrient concentrations were higher in the restored wetlands but lower than concentrations thought lethal to frogs. Complex mixtures of pesticides including up to 8 fungicides, some previously unreported in tissue, were detected with concentrations ranging from 0.08 to 1500 μg/kg wet weight. No significant differences in pesticide concentrations were observed between species, although concentrations tended to be higher in leopard frogs compared to chorus frogs, possibly because of differences in life histories. Our results provide information on habitat quality in restored wetlands that will assist state and federal agencies, landowners, and resource managers in identifying and implementing conservation and management actions for these and similar wetlands in agriculturally dominated landscapes. RightsWorks produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted. H I G H L I G H T S• Habitat quality was similar between restored and reference wetlands in Iowa.• Complex mixtures of pesticides are detected in frog tissues (liver and whole body).• The number of fungicides (up to 8) in frog tissues is largest reported to date.• Life history has the potential to impact pesticide bioaccumulation in frogs. Habitat loss and exposure to pesticides are likely primary factors contributing to amphibian decline in agricultural landscapes. Conservation efforts have attempted to restore wetlands lost through landscape modifications to reduce contaminant loads in surface waters and providing quality habitat to wildlife. The benefits of this increased wetland area, perhaps especially for amphibians, may be negated if habitat quality is insufficient t...

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Section: Introductionmentioning

confidence: 99%

Pesticide concentrations in frog tissue and wetland habitats in a landscape dominated by agriculture

Smalling

Reeves

Muths

et al. 2015

Science of The Total Environment

124

View full text Add to dashboard Cite

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“…), beldroega (Portulaca oleracea L.), entre outras, durante um período de até cinco meses (Hertwig, 1977;Gelmini, 1991;Khouri, 2007;Colla et al, 2008). Os impactos da sua presença na água e seus efeitos ecotoxicológicos já são bastante conhecidos (Hayes et al, 2002;Christin et al, 2004;Weiner et al, 2004;Ma et al, 2006;Murphy et al, 2006).…”

Section: Introductionunclassified

Associação de Rhizobium sp. a duas leguminosas na tolerância à atrazina

2011

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Association of Rhizobium sp. with two legumes on atrazine toleranceThe association of bacteria with plants has been studied as a possible emerging technology for phytoremediation of contaminants, including herbicides, which pose as a threatening to environmental quality due to their recalcitrance. The aim of this study was to assess the tolerance of dwarf mucuna (Stizolobium deeringianum Bort) and black mucuna (Stizolobium aterrimum Piper & Tracy) inoculated and uninoculated with Rhizobium to the herbicide atrazine. The treatments were: plants with inoculant + 0.1 g/m 2 , 0.2 g/m 2 atrazine, and without atrazine (T1, T2 and T3, respectively), plants without inoculant + 0.1 g/m 2 , 0.2 g/m 2 atrazine and without atrazine (T4, T5 and T6, respectively). The experiment was arranged in a completely randomized design, with three replications. Plants were grown in a

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“…Triazinic compounds such as atrazine, simazine, propazine, as well their metabolites, mainly 2-hydroxyatrazine, diaminochlorotriazine, deethylatrazine and deisopropylatrazine, were shown to induce mammary gland tumors in Sprague-Dawley (SD) female rats (Stevens et al, 1994). Atrazine has also been suggested to be a potential disruptor of normal sexual development in male frogs (Hayes et al, 2002;Murphy et al, 2006) as well as to alter some aspects of the immune response (Christin et al, 2004). In 2007, the United States Environmental Protection Agency (USEPA) began reviewing several epidemiological cancer studies concerning atrazine and its possible association with carcinogenic effects in humans.…”

Section: Atrazinementioning

confidence: 99%