2020
DOI: 10.1016/j.heares.2020.108068
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Abstract: Highlights We used highpass masking to record ABRs and FFRs from low-frequency regions. Wave I ABRs with highpass masking are not consistent with low-frequency synaptopathy. Wave I ABRs without highpass masking are consistent with high-frequency synaptopathy. Highpass-masked FFRs do not provide evidence of low-frequency synaptopathy.

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Cited by 16 publications
(20 citation statements)
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“…For the analyses the TCNE was log-transformed using base 10, so that a unit difference in the log 10 -transformed TCNE corresponds to a tenfold difference in noise exposure energy. Further details of the noise exposure interview are available in a previous publication ( Carcagno and Plack, 2020 ).…”
Section: Methodsmentioning
confidence: 99%
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“…For the analyses the TCNE was log-transformed using base 10, so that a unit difference in the log 10 -transformed TCNE corresponds to a tenfold difference in noise exposure energy. Further details of the noise exposure interview are available in a previous publication ( Carcagno and Plack, 2020 ).…”
Section: Methodsmentioning
confidence: 99%
“…Audiometric thresholds were measured for pure tones at octave frequencies from 0.125 to 8 kHz (clinical frequency range) as well as for pure tones at 12 and 16 kHz (extended high-frequency range) using a two-interval two-alternative forced-choice (2I-2AFC) task with an adaptive two-down one-up transformed up-down procedure tracking the correct point on the psychometric function ( Levitt, 1971 ). Further details of the procedure are available in a previous publication ( Carcagno and Plack, 2020 ).…”
Section: Methodsmentioning
confidence: 99%
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“…Evidence of noise-induced cochlear synaptopathy has been inconsistent in studies enrolling human participants (for review see 15,93), although evidence consistent with age-related synaptopathy has been provided (70,88). There are ongoing efforts in this area and new data continue to emerge regarding age-and/or noise-induced cochlear synaptopathy (22,23,26,121,122).…”
Section: Introductionmentioning
confidence: 99%
“…In order to elucidate the relations between these measures, in the current study we exploited a rich dataset that we previously analyzed with the aim of finding signs of age-related cochlear synaptopathy (CS), or more generally, of age-related declines that could not be accounted for by loss of hearing sensitivity ( Carcagno, Plack, 2020 , Carcagno, Plack, 2021 ). This dataset includes tests of abilities close to real-world hearing abilities (speech reception, and assessment of preference for musical consonance, which for brevity will be referred to as tests of real-world hearing abilities), psychophysical tests of auditory temporal processing, and electrophysiological tests of subcortical auditory processing collected on a cross-sectional sample of 102 participants ranging in age from 19 to 74 years.…”
Section: Introductionmentioning
confidence: 99%