Carbon burial in lake sediments has a profound impact on the global carbon cycle. In this study, the burial characteristics of organic carbon (OC) in typical sediments from the Poyang basin over the past hundred years were investigated and the influencing factors and driving mechanism were determined. The results showed that carbon burial in the Poyang basin sediments was mainly driven by human activities, whereas the change in the OC accumulation rate was related to precipitation, forest land area, water area, construction land area, urbanization rate, application of agricultural fertilizers, per capita GDP and population.