Ethanol occurs naturally in the decaying fruit in which many species of Drosophila (Diptera: Drosophilidae) breed, potentially generating selection for resistance to its toxic and sedating effects. Studies measuring mortality of flies exposed to a range of ethanol concentrations have shown that within Drosophila melanogaster Meigen, populations from temperate regions are more ethanol resistant than ancestral tropical African populations. The high ethanol resistance of temperate D. melanogaster presents a puzz…
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