Effectiveness of resilience-promoting interventions in adolescents with diabetes mellitus: a systematic review and meta-analysis

Abstract

Background This study aimed to analyze the efficacy of resilience-promoting interventions among adolescents and youth aged 10–24 years with any type of diabetes. Methods A systematic literature search was performed using the PubMed, Web of Science, Embase, Cochrane Library, CINAHL, and PsycINFO databases from inception to May 25, 2022. The Cochrane risk of bias tool (version 2) was used to assess the quality of the included studies. A meta-analysis was performed to calculate the pooled effects of resilience-promoting interventions. Results Nineteen articles were included covering an overall sample of 2048 adolescents with diabetes. When analyzing the effectiveness of resilience-promoting interventions, hemoglobin A1c (HbA1c) at six months [mean difference = − 0.47, 95% confidence interval (CI) = − 0.83 to − 0.12, P = 0.009] after the intervention was improved. However, long-term (≥ 12 months) improvement in HbA1c was not significant. In addition, comparing the control group, there were significant differences in the effect size for stress [standardized mean difference (SMD) = − 0.87, 95% CI = − 1.25 to -0.48, P < 0.05], self-efficacy (SMD = 0.50, 95% CI = 0.02–0.98, P = 0.04) and quality of life (SMD = 0.27, 95% CI = 0.03–0.51, P = 0.03). Conclusions Resilience-promoting intervention is a promising way for adolescent diabetes management to improve HbA1c, stress, self-efficacy, and quality of life. Incorporating resilience-promoting components into diabetes education and re-enforcing these contents every six months are recommended for implementation in clinical practice. Supplementary Information The online version contains supplementary material available at 10.1007/s12519-022-00666-7.

A Phase II Study Integrating a Single-Blind Safety Phase with a Double-Blind, Placebo-Controlled Randomized Phase, Assessing Single-Dose Intramuscular or Intranasal Administration to Evaluate the Safety and Immunogenicity of the Recombinant Vaccine Against COVID-19 (AVX/COVID-12 “Patria”) Based on an Active Newcastle Disease Viral Vector as a Heterologous Booster in Subjects with Evidence of Previous Immunity to SARS-CoV-2

“…For instance, a full vaccination scheme with a booster from Moderna shows 95% effectiveness, Pfizer demonstrates 95-100% (22,23), while AstraZeneca or Janssen exhibits 85-90% effectiveness (23). Additionally, the mRNA vaccine BNT162b2 has been reported to be 84.9% effective in preventing intensive care unit admission for COVID-19 in children and 95% in adolescents (24). Other studies indicate a 90.9% effectiveness of this vaccine against hospitalization and death caused by the Omicron BA.1 and BA.2 variants of SARS-CoV-2, while the AZ/ChAdOx-1-S vaccine showed 82.3% effectiveness (25).…”

Hubungan Antara Tingkat Resiliensi Dengan Kadar Glukosa Darah Sewaktu Remaja Dengan Dm Tipe 1

“…Di dalam konteks diabetes tipe 1, resiliensi tinggi dapat memiliki dampak positif pada pemeliharaan kadar glukosa darah yang normal melalui beberapa mekanisme kompleks (Luo et al, 2022). Sejalan dengan penelitian terkini, penelitian sebelumnya menyebutkan bahwa remaja dengan tingkat resiliensi tinggi cenderung memiliki kemampuan untuk mengatasi stres dan tekanan dengan lebih baik (Wu et al, 2023). Dalam konteks diabetes, stres dapat mempengaruhi kadar gula darah melalui pelepasan hormon stres seperti kortisol dan adrenalin (Sharma et al, 2022).…”

“…Resiliensi remaja yang mengidap diabetes tipe 1 (T1D) terhadap berbagai faktor pemicu stres merupakan aspek krusial dalam mencapai keberhasilan manajemen diri yang berujung pada stabilnya tingkat glukosa darah dan mengurangi risiko komplikasi baik dalam jangka waktu yang singkat maupun panjang (Wu et al, 2023). Konsep resiliensi ini mencerminkan kemampuan individu untuk menjaga kesehatan fisik dan psikologisnya ketika dihadapkan pada situasi stres, khususnya pada remaja yang hidup dengan T1D.…”

Serious games for mental health promotion in adolescents with chronic diseases: a scoping review

“…Currently, numerous interventions have been developed to enhance the mental health of adolescents diagnosed with chronic diseases. Most of these interventions were face-to-face counseling or group psychoeducation (Wu et al , 2022). However, for teens, online or serious game is the form of mental health promotion intervention they are more willing to accept.…”