Effectiveness of Fortification of Drinking Water with Iron and Vitamin C in the Reduction of Anemia and Improvement of Nutritional Status in Children Attending Day-Care Centers in Belo Horizonte, Brazil

Rocha, Daniela da Silva; Capanema, Flávio Diniz; Netto, Michele Pereira; Nogueira‐de‐Almeida, Carlos Alberto; Franceschini, Sylvia do Carmo Castro; Lamounier, Joel Alves

doi:10.1177/156482651103200405

Cited by 16 publications

(8 citation statements)

References 21 publications

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“…Their main role is to deliver methylene group for synthesis of necessary thymidylate. The effect of vitamin C is unquestionable, since it facilitates iron assimilation and participates in haemoglobin synthesis and folic acid and copper conversion to active forms [18, 19]. …”

Section: Discussionmentioning

confidence: 99%

Risk of Anaemia in Population of Healthy Young People Inhabiting a Region in Central Europe

Gutowska¹,

Seidler²,

Mierzwa³

et al. 2013

Journal of Nutrition and Metabolism

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It is quite unbelievable but significant percentage of young healthy women is at risk of anaemia despite proper nutritional state. In this study we decided to determine the lack or excess of which nutrients in a diet can lead to any effects. The major cause of anaemia is not, as in many studies on nutritional status, the deficiency in iron in a diet. Iron intake in women with anaemia exceeded AI (Adequate Intake) level. 120 people took part in the study. Average HGB concentration in female group amounted to 12.45 g/dL and in male group to 14.35 g/dL. Anaemia was determined in 29% women and 4.2% men. In group of women with anaemia a statistically higher intake of SFA, cholesterol, and sucrose and lower intake of pyridoxine, folacin, niacin, and vitamin E, Mn, Cu, Zn, Fe, and Mg were determined. In a group of men with low haemoglobin concentration a statistically higher intake of sucrose but lower intake of fat, especially SFA and MUFA, vitamin C and zinc were observed. Therefore, together with anaemia in the group of women there are coexisting deficiencies in other nutrients, as compared to the group of men. Prevention in both groups should include various supplements.

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Section: Discussionmentioning

confidence: 99%

Risk of Anaemia in Population of Healthy Young People Inhabiting a Region in Central Europe

Gutowska¹,

Seidler²,

Mierzwa³

et al. 2013

Journal of Nutrition and Metabolism

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“…Vitamin C can create a more acidic environment in the stomach and prevent the oxidization of ferrous iron to ferric iron. 10 However, in a series of 12 individuals treated with iron during intake of a regular or vitamin C–supplemented diet, 8 the effect of vitamin C on promoting iron absorption from a complete diet was far less pronounced than that from a single meal. The facilitating impact of vitamin C with food on iron status is minimal.…”

Section: Introductionmentioning

confidence: 99%

The Efficacy and Safety of Vitamin C for Iron Supplementation in Adult Patients With Iron Deficiency Anemia

Zhao

et al. 2020

JAMA Netw Open

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Key Points Question Are the effects of oral iron supplements alone equivalent to a regimen of oral iron supplements plus vitamin C in the treatment of iron deficiency anemia? Findings In this randomized clinical trial that included 440 adults with iron deficiency anemia, the mean change in hemoglobin level after 2 weeks was 2.00 g/dL in the oral iron supplements plus vitamin C group, compared with 1.84 g/dL in the oral iron supplements–only group. This difference met prespecified criteria for equivalence. Meaning The use of oral iron supplements alone is comparable to a regimen of vitamin C supplemented with oral iron for patients with iron deficiency anemia.

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“…32 There is also some research on the addition of iron and zinc. [33][34][35][36][37][38] Our study shows that in populations with low calcium intake, more than one strategy might be required so that all population groups reach adequate calcium intake levels. Strategies like calcium supplementation are usually not adequate for a whole population as they rely on adherence and access to supplements.…”

Section: Discussionmentioning

confidence: 83%

“…Opportunities to use water as a vehicle to increase mineral intake at the population level are limited; water fluoridation to improve dental health is the most studied 32 . There is also some research on the addition of iron and zinc 33–38 …”

Section: Discussionmentioning

confidence: 99%

Calcium concentration of drinking water to improve calcium intake: A simulation study

Cormick

Romero

Matamoros

et al. 2023

Annals of the New York Academy of Sciences

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The risk of inadequate calcium intake is a worldwide problem. We performed a simulation exercise on the impact, effectiveness, and safety of increasing calcium levels in drinking water using the 2019 Health and Nutrition National Survey of Argentina, which provides water intake and water sources data at the individual level. We simulated the distribution of calcium intake assuming a calcium concentration of 100 mg of calcium per liter of tap water and 400 mg of calcium per liter of bottled water. After the simulation, all population groups had a slightly improved calcium intake. Higher impacts were observed in adults, as reported water intake was higher in adults 19–51 years old. In young adult women, the estimated calcium intake inadequacy decreased from 91.0% to 79.7% when calcium was increased in tap water and to 72.2% when calcium was increased in tap and bottled water. The impact was lower in adolescents and older adults who have higher calcium recommendations and reported lower water intake. Increased calcium concentration of water could improve calcium intake in Argentina, especially in adults as their reported water intake is higher. Combining more than one strategy to improve calcium intake might be required for countries like Argentina with low calcium intake.

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Effectiveness of Fortification of Drinking Water with Iron and Vitamin C in the Reduction of Anemia and Improvement of Nutritional Status in Children Attending Day-Care Centers in Belo Horizonte, Brazil

Abstract: Fortification of water with iron and vitamin C significantly reduced the prevalence of anemia and improved nutritional status among children attending day-care centers.

Cited by 16 publications

References 21 publications

Risk of Anaemia in Population of Healthy Young People Inhabiting a Region in Central Europe

Risk of Anaemia in Population of Healthy Young People Inhabiting a Region in Central Europe

The Efficacy and Safety of Vitamin C for Iron Supplementation in Adult Patients With Iron Deficiency Anemia

Calcium concentration of drinking water to improve calcium intake: A simulation study

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