Effectiveness of a nurse-led telephone follow-up in the therapeutic management of patients receiving oral antineoplastic agents: a randomized, multicenter controlled trial (ETICCO study)

Nurse-led telehealth interventions for symptom management in patients with cancer receiving systemic or radiation therapy: a systematic review and meta-analysis

“…In the search completed on March 21, 2021, there were 7749 citations after duplicates were removed, 178 full-text studies were assessed, and 10 were included (Fig. 3 ) [ 11 , 14 , 17 , 23 , 38 – 43 ]. The most common reasons for exclusion during full-text review were trial protocols or ineligible interventions (Online Resource 1 ).…”

“…Eight RCTs and 2 quasi-experimental studies (CBA design) were included, which evaluated 2315 participants (Table 1 ). Five studies were conducted in the USA [ 11 , 17 , 41 – 43 ] and one each in Canada [ 14 ], France [ 38 ], Italy [ 39 ], Hong Kong [ 23 ], and Turkey [ 40 ]. Seven studies evaluated heterogeneous samples of patients with cancer, two studies included patients with lung cancer [ 40 , 43 ], and one study included women with breast cancer [ 23 ].…”

“…Seven studies evaluated heterogeneous samples of patients with cancer, two studies included patients with lung cancer [ 40 , 43 ], and one study included women with breast cancer [ 23 ]. Nine studies evaluated adults (18 years or older) [ 11 , 17 , 23 , 38 – 43 ] and one study evaluated adolescents (12–18 years) [ 14 ].…”

“…Nine studies evaluated adults (18 years or older) [ 11 , 17 , 23 , 38 – 43 ] and one study evaluated adolescents (12–18 years) [ 14 ].…”

“…In five studies, nurses or NPs were alerted if self-reported symptoms increased rapidly or were above a pre-defined threshold (reactive intervention) [ 11 , 14 , 17 , 41 , 43 ]. In the other five studies, nurses or NPs contacted patients at pre-defined times (scheduled interventions) [ 23 , 38 – 40 , 42 ]. Scheduled interventions only used the telephone as a mode of delivery, whereas reactive interventions used telephone-, web-, or smartphone-based systems.…”