Effectiveness of a new non-hydrogen peroxide bleaching agent after single use - a double-blind placebo-controlled short-term study

Abstract

Tooth whitening represents perhaps the most common aesthetic procedure in dentistry worldwide. The efficacy of bleaching depends on three aspects: bleaching agent, bleaching method, and tooth color.Objective:This in vivo study aimed to examine whitening effects on frontal teeth of the upper and lower jaws using an over-the-counter (OTC) non-hydrogen peroxide bleaching agent in comparison to a placebo after one single use.Material and methods:Forty subjects (25 female; 15 male) participated in this double-blind randomized placebo-controlled trial. The subjects were randomly allocated to two groups (n=20). The test group received the OTC product (iWhite Instant) and the placebo group received an identically composed product except for the active agents. Each subject was treated with a prefilled tray containing iWhite Instant or the placebo for 20 minutes. The tooth shade of the front teeth (upper and lower jaws) was assessed before (E_0), immediately after (E_1) and 24 h after treatment (E_2), using a shade guide (VITA classical). Statistical testing was accomplished using the Mann-Whitney U test (p<0.001). The dropout rate was 0%.Results:There were no significant differences at E_0 between placebo and test groups regarding the tooth color. Differences in tooth color changes immediately after (ΔE1_0) and 24 h after treatment (ΔE2_0) were calculated for both groups. The mean values (standard deviations) of tooth color changes for ΔE1_0 were 2.26 (0.92) in the test group and 0.01 (0.21) in the placebo group. The color changes for ΔE2_0 showed mean values of 2.15 (1.10) in the test group and 0.07 (0.35) in the placebo group. For ΔE1_0 and ΔE2_0 significant differences were found between the groups.Conclusion:In this short-term study, the results showed that a non-hydrogen peroxide bleaching agent has significant whitening effects immediately and 24 h after a single-use treatment.

Knowledge, practices, and perceptions about tooth whitening among female population in Saudi Arabia – A cross-sectional study

“…Hydrogen peroxide (H 2 O 2 ) is the active ingredient that is commonly used in most tooth-bleaching products. [ 4 16 ] H 2 O 2 usually causes undesirable effects in the oral cavity such as mucosal irritation, teeth sensitivity, microcracks on enamel, root resorption, and pulpitis. [ 17 ] People need to understand these adverse effects well in advance to prepare themselves, thus minimizing the complaints about treatments done by dentists.…”

Izbjeljivanje zuba tehnikom „take-home“

“…Prije nego što se počne s izbjeljivanjem potrebno je pacijentu ukloniti sve meke (plak ili biofilm) i tvrde naslage (kamenac) jer u protivnom izbjeljivanjem nećemo postići željeni učinak 11 . Naime, zubni kamenac je krem-bijela, tamnožuta ili smećkasta nakupina koja nastaje mineralizacijom bakterijskog plaka, tj.…”

“…Mnogi pacijenti su već zadovoljni bojom svojih zuba nakon temeljitog čišćenja u ordinaciji, čime se osim plaka i zubnog kamenca uklanja i većina egzogenih diskoloracija, a ostali se odlučuju za izbjeljivanje. U svakom slučaju, profesionalno čišćenje je pretpriprema odnosno prvi korak k izbjeljivanju 11,13 U ordinaciji dentalne medicine uklanjanje mekih zubnih naslaga provodi se četkicama, gumicama i abrazivnim pastama, dok je pjeskarenje pokazalo izvrsne rezultate u uklanjanju plaka na teško dostupnim mjestima te uklanjanju supragingivnih pigmentacija egzogenog podrijetla. Pjeskarenje uključuje izbacivanje mlaza čestica bikarbonata ili eritritola i vode pod tlakom na površinu zuba.…”

Nitrogen-Doped Titanium Dioxide Mixed with Calcium Peroxide and Methylcellulose for Dental Bleaching under Visible Light Activation

“…Hydrogen peroxide is the most common active ingredient in dental bleaching products, due to its ability to release free radicals [ 5 ]. These free radicals trigger the oxidation and splitting of pigmented organic molecules into smaller molecules.…”

Evaluation of Three Different Bleaching Agents in Permanent and Primary Teeth: An In Vitro Study

“…5 Hydrogen peroxide is a strong oxidizing agent that can penetrate dentin and releases oxygen, which further breaks the double bonds of organic and inorganic compounds inside the dentinal tubules causing decolorization of the stains. 6 One of the main undesirable consequences of intracoronal bleaching with HP was external cervical root resorption of the tooth. The excessive diffusion of HP into the periradicular tissues, possibly through cemental defects, was the possible reason behind the cervical root resorptions in the bleached teeth.…”