Effective factors on 3-year mortality of operated gastric cancer at Modarres Hospital during 5 years

Gholizade, Barmak; Malekpour, Nasser

doi:10.15171/jarcm.2017.011

Cited by 1 publication

(1 citation statement)

References 5 publications

(6 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The survival rate of patients with gastric cancer depends on various factors such as age, stage of disease, type of treatment and histopathology, location and degree of tumor differentiation (6). According to the results of the study by Gholizadeh and Malekpour, the mortality rate was directly correlated with the higher stage (7). Among other poor prognostic factors of gastric cancer, more…”

Section: Introductionmentioning

confidence: 98%

The five-year survival of gastric cancer patients with a focus on its prognostic factors

et al. 2021

View full text Add to dashboard Cite

Introduction: Despite extensive advances in the early diagnosis and treatment of gastric cancer, it is still one of the most common causes of death worldwide. In addition to stage and recurrence, the degree of tumor differentiation affects the survival of patients. Objectives: The current study was conducted to investigate the prognostic factors and survival rate of patients with gastric cancer. Patients and Methods: The current prospective study was conducted on patients with gastric cancer from 2010 to 2017 in Imam Khomeini and Apadana hospitals in Ahvaz, Southwest of Iran. For each patient, curative (total or subtotal gastrectomy with D2 lymphadenectomy) or palliative surgery (partial gastrectomy and gastrojejunostomy) were carried out based on clinical indications. Then Cox model was used to analyze factors affecting survival and the Kaplan-Meier test was also utilized to analyze the five-year survival of patients with SPSS version 21. Results: Around 154 patients with gastric cancer, including 101 males (65.6%), with a mean age of 62.21±13.76 years, were studied. The two- and five-year overall survival (OS) of patients were 57.7% and 28.5%, respectively (median OS=28 m). Lower stage, well-differentiated tumors, absence of metastasis, lack of recurrence, receiving adjuvant chemotherapy and curative surgery were significantly associated with greater OS (P<0.05). Conclusion: OS rate of patients with gastric cancer undergoing surgery, especially in the ones with high-grade tumors, metastasis and recurrence, is relatively low, hence careful implementation of screening programs should be considered as the most important preventive strategy.

show abstract

Section: Introductionmentioning

confidence: 98%