Effect on the Skin of Emotional and Nervous States

Stokes, John H.

doi:10.1001/archderm.1932.01450030476014

Cited by 27 publications

(2 citation statements)

References 11 publications

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“…The intestine-brain-skin axis hypothesis was first proposed 80 years ago by the dermatologists John H. Stokes and Donald M. Pillsbury [ 70 ] and has recently become of interest once again. Briefly, the hypothesis is centered on the capacity of emotional states (e.g., depression and anxiety) to alter normal intestinal microbiota, to increase intestinal permeability and to contribute to systemic inflammation.…”

Section: Possible Mechanisms Involved In the Skin Effects Of Oral mentioning

confidence: 99%

Message in a Bottle: Dialog between Intestine and Skin Modulated by Probiotics

Friedrich

Paz

Leoni

et al. 2017

IJMS

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At the beginning, probiotics were used exclusively for gastrointestinal conditions. However, over the years, evidence has shown that probiotics exert systemic effects. In this review article, we will summarize recent reports that postulate probiotic treatment as an efficient one against skin pathologies, such as cancer, allergy, photoaging and skin infections. The focus will be restricted to oral probiotics that could potentially counteract the ultraviolet irradiation-induced skin alterations. Moreover, the possible underlying mechanisms by which probiotics can impact on the gut and exert their skin effects will be reviewed. Furthermore, how the local and systemic immune system is involved in the intestine-cutaneous crosstalk will be analyzed. In conclusion, this article will be divided into three core ideas: (a) probiotics regulate gut homeostasis; (b) gut and skin homeostasis are connected; (c) probiotics are a potentially effective treatment against skin conditions.

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Section: Possible Mechanisms Involved In the Skin Effects Of Oral mentioning

confidence: 99%

Message in a Bottle: Dialog between Intestine and Skin Modulated by Probiotics

Friedrich

Paz

Leoni

et al. 2017

IJMS

View full text Add to dashboard Cite

show abstract

“…Symptoms of intestinal discomfort attributed to carbohydrate intolerance (Kendall, 1926) have long been recognized as a feature of rosacea (Eastwood, 1928), but attempts to alleviate them and improve the facial flushing with a low-carbohydrate diet have been only partially successful (Stokes and Beerman, 1932).…”

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confidence: 99%