Effect of Vehicle and Agitation Methods on the Penetration of Calcium Hydroxide Paste in the Dentinal Tubules

Barbosa, Mariana de Almeida; Oliveira, Kauhanna Vianna de; Santos, Vinícius Rodrigues dos; Silva, Wander José da; Tomazinho, Flávia Sens Fagundes; Baratto‐Filho, Flares; Gabardo, Marilisa Carneiro Leão

doi:10.1016/j.joen.2020.03.026

Cited by 13 publications

(24 citation statements)

References 29 publications

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“…Considering this informations, the similar removal efficiency of water-based medicament and viscous-based medicament obtained in the current study can be attributed to the fact that glycerin in the viscous-based medicament keeps the paste moist. It was also shown in a study using confocal laser scanning microscopy, the penetration into dentinal tubules in the apical region of CaOH pastes prepared with aqueous (distilled water) and viscous (propylene glycol) vehicles were similar ( 23 ). They attributed this to the fact that the small diameter, sclerotic, small and fewer tubules and difficulty to reach for the tip of the agitation instruments at the apical region.…”

Section: Discussionmentioning

confidence: 77%

“…This study was designed with a standardised size and location of the groove model using a scoring system. The standardised grooves create standardised conditions to provide reliable information about the amounts of medicament before the irrigation ( 23 ). Moreover, the design provides an advantage concerning the evaluation, with high-quality intra-examiner reproducibility and good inter-examiner agreement ( 24 ).…”

Section: Discussionmentioning

confidence: 99%

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Removal of Calcium Hydroxide Pastes Containing NMP, Local Anaesthesia, Glycerine, and Methylcellulose from Artifical Radicular Grooves: An in-vitro Study

Ali¹

2021

Eur Endod J

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Objective: To compare the removal of calcium hydroxide (CaOH) pastes containing N-Methyl-2-pyrrolidone (NMP), lidocaine, glycerine, methylcellulose, or water from artificially created grooves. Methods: In this study, 115 human single-rooted maxillary incisors with single and straight root canals were prepared using a rotary file up to size 40/.04 and split longitudinally. A longitudinal groove was created from 2 to 5 mm from the apex and filled with CaOH combined with different vehicles. The specimens were divided among 5 experimental groups according to the vehicle as follows: distilled water, lidocaine, glycerine, methylcellulose, and NMP. The two halves were re-attached, and the canals were flushed with 10 ml of 17% EDTA for 60 seconds. The residual amount of CaOH was scored using a stereomicroscope at 8× magnification. Statistical significance was set at P<0.05. Results: The NMP-based group exhibited significantly less residual medicament compared to the distilled water (P<0.05), while there were no statistically significant differences among the methylcellulose-, lidocaine-, and glycerine-based groups and distilled water (P>0.05). Conclusion: The vehicle is an important factor in the successful removal of CaOH medicament from the root canals. Within the limitations of the present study, the NMP-based CaOH medicament exhibited better removal efficacy than the distilled water. However, the cleaning success of the methylcellulose-, lidocaine-, and glycerine-based groups was similar to that of distilled water.

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Section: Discussionmentioning

confidence: 77%

Section: Discussionmentioning

confidence: 99%

Removal of Calcium Hydroxide Pastes Containing NMP, Local Anaesthesia, Glycerine, and Methylcellulose from Artifical Radicular Grooves: An in-vitro Study

Ali¹

2021

Eur Endod J

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“…However, in that study, the assessments were performed with materials in powder form, which does not represent clinical use, as the combination of Ca(OH) 2 [ 4 6 16 ] or ZnO with different vehicles is necessary to obtain an adequate consistency of the material [ 10 17 ]. Specifically, in this study, the paste consistency was chosen to facilitate insertion in immature teeth with large canals, minimize the dispersion of the materials into the tissues, and retain the material in the desired area for a longer time [ 18 ]. Thus, an initial test was performed in order to verify the consistency of the material after manipulation with the proposed vehicle, demonstrating that the ZnO:0.7Ca nanocrystals did not have the desired consistency after manipulation.…”

Section: Discussionmentioning

confidence: 99%

“…According to Mohammadi and Dummer [ 35 ], viscous vehicles promote the slow and sustained release of Ca 2+ and OH - ions from Ca(OH) 2 pastes compared with aqueous vehicles. In addition, the use of viscous vehicles has been suggested to optimize the intratubular penetration of intracanal medications [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

Calcium-doped zinc oxide nanocrystals as an innovative intracanal medicament: a pilot study

et al. 2022

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Objectives This study investigated the cytotoxicity, radiopacity, pH, and dentinal tubule penetration of a paste of 1.0% calcium-doped zinc oxide nanocrystals (ZnO:1.0Ca) combined with propylene glycol (PRG) or polyethylene glycol and propylene glycol (PEG-PRG). Materials and Methods The pastes were prepared by mixing calcium hydroxide [Ca(OH) 2 ] or ZnO:1.0Ca with PRG or a PEG-PRG mixture. The pH was evaluated after 24 and 96 hours of storage in deionized water. Digital radiographs were acquired for radiopacity analysis and bubble counting of each material. The materials were labeled with 0.1% fluorescein and applied to root canals, and images of their dentinal tubule penetration were obtained using confocal laser scanning microscopy. RAW264.7 macrophages were placed in different dilutions of culture media previously exposed to the materials for 24 and 96 hours and tested for cell viability using the MTT assay. Analysis of variance and the Tukey test ( α = 0.05) were performed. Results ZnO:1.0Ca materials showed lower viability at 1:1 and 1:2 dilutions than Ca(OH) 2 materials ( p < 0.0001). Ca(OH) 2 had higher pH values than ZnO:1.0Ca at 24 and 96 hours, regardless of the vehicle ( p < 0.05). ZnO:1.0Ca pastes showed higher radiopacity than Ca(OH) 2 pastes ( p < 0.01). No between-material differences were found in bubble counting ( p = 0.0902). The ZnO:1.0Ca pastes had a greater penetration depth than Ca(OH) 2 in the apical third ( p < 0.0001). Conclusions ZnO:1.0Ca medicaments presented higher penetrability, cell viability, and radiopacity than Ca(OH) 2 . Higher values of cell viability and pH were present in Ca(OH) 2 than in ZnO:1.0Ca.

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“…[ 1 ] Besides the antimicrobial activity, it is important to understand the benefit of using a particular formulation. [ 2 3 ]…”

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confidence: 99%

From the Desk of the Editor......The Vehicle for Calcium Hydroxide

Singh

2020

J Conserv Dent

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Effect of Vehicle and Agitation Methods on the Penetration of Calcium Hydroxide Paste in the Dentinal Tubules

Cited by 13 publications

References 29 publications

Removal of Calcium Hydroxide Pastes Containing NMP, Local Anaesthesia, Glycerine, and Methylcellulose from Artifical Radicular Grooves: An in-vitro Study

Removal of Calcium Hydroxide Pastes Containing NMP, Local Anaesthesia, Glycerine, and Methylcellulose from Artifical Radicular Grooves: An in-vitro Study

Calcium-doped zinc oxide nanocrystals as an innovative intracanal medicament: a pilot study

From the Desk of the Editor......The Vehicle for Calcium Hydroxide

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