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Cited by 42 publications
(11 citation statements)
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“…The failure of production of antibodies to streptokinase and streptolysin 0 in those patients "successfully" treated with penicillin (Group III) is apparent from inspection of Tables I and II, and (21), and by Weinstein and Tsao (22). In contrast to the flattened curves seen in Figures 1 and 2 for this group (Group III), the average gamma globulin levels ( Figure 3) show a rise comparable to those of Groups I and IV.…”
mentioning
confidence: 40%
“…The failure of production of antibodies to streptokinase and streptolysin 0 in those patients "successfully" treated with penicillin (Group III) is apparent from inspection of Tables I and II, and (21), and by Weinstein and Tsao (22). In contrast to the flattened curves seen in Figures 1 and 2 for this group (Group III), the average gamma globulin levels ( Figure 3) show a rise comparable to those of Groups I and IV.…”
mentioning
confidence: 40%
“…Previous studies have established the fact that penicillin treatment of acute streptococcal pharyngitis results in a marked suppression of antibody formation (1,2,3). This is in contrast to the failure of penicillin treatment to alter the immune response in patients with pneumococcal pneumonia (4).…”
mentioning
confidence: 99%
“…It is apparent that the quantity of antigen present in the usual patient with pneumococcal pneumonia before penicillin treatment is instituted is sufficient to stimulate antibody formation. This may not be the case in streptococcal infections in which early therapy with penicillin will apparently inhibit the antistreptolysin response (25)(26)(27)(28). As yet, however, an insufficient number of patients with pneumococcal infections treated within less than seven hours of onset has been observed to determine the effect of such early penicillin therapy on the immune response.…”
Section: Discussionmentioning
confidence: 89%