Effect of two periodontal treatment modalities in patients with uncontrolled type 2 diabetes mellitus: A randomized clinical trial

Abstract

Periodontal therapy had the greatest impact on HbA1c reduction on patients with an HbA1c > 9% regardless of treatment modality. Both modalities resulted in significant improvements in periodontal parameters.

The effects of non‐surgical periodontal therapy on glycemic control in diabetic patients: A randomized controlled trial

“…The current study demonstrated that NSPT can significantly reduce the level of HbA1c in T2DM patients with chronic periodontitis. This is in agreement with Quintero et al () who studied the impact of two NSPT modalities in T2DM patients with chronic periodontitis and reported that better periodontal clinical parameter and HbA1c level improvements were achieved with both NSPT modalities. In the present study, the explanation for these results may be attributed to the elevated serum level of IL‐6, IL‐1, and TNF‐a that, associated with chronic periodontitis, could antagonize the action of insulin (Calle & Fernandez, ) and increase the insulin resistance (Tunes, Foss‐Freitas, & Nogueira‐Filho, ).…”

“…Charting for the full‐mouth periodontium using a periodontal probe (Hu‐Friedy) was performed by the same specialist (SH). This includes PD (linear distance from margin of gingiva to base of pocket), CAL (the linear measurement from the cement–enamel junction to the base of the pocket), bleeding on probing (monitored as the percentage of areas that bleeding occurs after probing by 15 s), and the visible dental plaque that assessed by passing a periodontal probe at four sites (buccal, lingual, mesial, and distal) for each tooth and recorded as yes/no (Quintero et al, ). The bleeding on probing (BOP), CAL, and PD were recorded for all teeth at six sites for each tooth after third molar exclusion.…”

Periodontal disease and its impact on general health in Latin America. Section II: Introduction part II

“…12 In this context, periodontal treatment has been shown to reduce short-term levels of systemic markers of inflammation directly related to the etiopathogenesis of CVD. 28 A bidirectional relationship between periodontal disease and DM has been proposed (31). Indeed, periodontitis may impair glycemic control in DM patients 29 and periodontal treatment may improve glycemic control in these patients.…”

“…12 A recent study conducted in Chile reported that periodontal therapy led to a reduction in the level of HbA1c in DM patients with HbA1c > 9%, irrespective of the type of periodontal treatment. 31 Latin America strategies to increase the awareness of periodontal diseases Currently, various cultural and socio-economic barriers to professional care prevent the population from applying correct preventive approaches, receiving early diagnosis and seeking timely treatment, resulting in limited progress in improving periodontal health. 32 Periodontal disease is socially determined.…”

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“…9 Patients with T2DM have a greater prevalence, extent, and severity of CP than non-diabetic subjects. 10 The accumulation of anaerobic gram-negative bacteria can cause the CP and formation of calculus. CP is a multifactorial, chronic inflammatory disorder and if it is not treated, it may lead to non-reversible damages of oral supportive tissues (periodontal ligament, cementum, and alveolar bone) surrounding the teeth and finally result in tooth loss.…”