Effect of Temperature on Survival of Bacteria in Blood for Transfusion

James, J. D.; Stokes, E. Joan

doi:10.1136/bmj.2.5058.1389

Cited by 26 publications

(7 citation statements)

References 10 publications

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“…It is generally assumed that approximately 2 0 /0 of preserved blood is bacterially contaminated even with strict control [156,204,721,778,1031,1134] and that the number of serious reactions resulting from infusion of bacterially contaminated blood is greater than the complications caused by incompatibility [335,987]. LITWIN et al [912] have pointed out the synergistic toxic effect of gramnegative bacteria and free hemoglobin.…”

Section: Reactions Due To Bacterial Contaminationmentioning

confidence: 99%

Blood Replacement

Gruber¹

1969

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All rights reserved. No part of this book may be translated or reproduced in any form withoutwritten permission from Springer-Verlag. © by Springer-Verlag Berlin Heidelberg 1969. Library of Congress Catalog Card Number 69-16845Softcover reprint of the hardcover 1st edition 1969The use of general descriptive names, trade marks, etc. in this publication, even if the former are not especially identified, is not be taken as a sign that such names, as understood by the Trade Marks and Merchandise Act, may accordingly be used freely by anyone. Title-No. 1551 Dedicated to my wife LisaEs wurde fertig in Deiner Hut. Bleib Du mir auf dieser Erden, so 5011 alles fertig werden. THOMAS MANN ForewordThe manifold problems of shock are still of great importance, diagnostic and therapeutic experience of the "severely ill" being supplied with new information almost every month. In the 5 periodicals which have found their way to my desk during the past few days there are no less than 10 interesting articles on questions concerning shock research [see Bibliography 41 b, 53 a, 60 a, 192 a, 242 a, 350 b, 810 a, 941 a, 1069 a, 1082 a]. The most urgent point still is to maintain as complete as possible the objective catalog of the various shock manifestations found in man and in animals -yet at the same time to view interpretations of these phenomena in their relative and temporal "truth".Problems of shock research are not only interesting for their scientific value but also for their clinical implication. In particular, almost every practicing physician is facing problems of blood replacement very frequently. The effective or circulating blood volume remains an important theoretical and therapeutic problem in the shock field. For years, U. F. GRUBER has pursued this question clinically and experimentally. This volume deals with the world literature in an exceptionally thorough manner. This book is made more than a compilation by including a long list of original work done with F. D. MOORE in Boston, in the Surgical Department in Chur, with L. E. GELIN and S. E. BERGENTZ in Goteborg and in the Laboratory for Experimental Surgery in Davos; judgements are made on the basis of original studies, and essential points are separated from unimportant ones. This volume will be welcomed by the medical profession because it carefully treats vital questions concerning this complicated, much-discussed, and in part contested field, considering that today, along with various forms of blood and several plasma preparations, there are more than 40 different plasma replacement substances available with various physico-chemical, biological and pharmacological properties. Older preparations have been abandoned, others modified, and new ones appear.A comparative evaluation of the chemical characteristics, the range of indication and the therapeutic effectiveness of these solutions suggests itself particularly at this time because in recent years the use of large amounts of balanced electrolyte solutions tended to reverse the principles of blood replaceme...

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Section: Reactions Due To Bacterial Contaminationmentioning

confidence: 99%

Blood Replacement

Gruber¹

1969

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“…Staphylococcus epidermidis und andere koagulasenegative Staphy- [30]. Mit hoher Wahrscheinlichkeit ist davon auszugehen, daß von der Haut des Spenders in die Blutspende gelangte Staphylokokken in der überwiegenden Mehrzahl der Fälle -trotz Einschränkung der Komplementaktivierung wegen der Kalziumbindung durch Zitrat -über Opsonophagozytose eliminiert werden [31]. Dennoch werden koagulasenegative Staphylokokken nach Literaturangaben [1,8,12,15,17,27] und nach eigenen Erfahrungen regelmäßig bei Sterilitätstestungen von Blutkomponenten nachgewiesen.Andererseits wird in der Literatur über eine Reihe von schweren bis tödlichen transfusionsbedingten Infektionen durch diese Keime berichtet [24,[32][33][34][35][36][37][38].…”

Section: Risikobewertung Von Mikroorganismenunclassified

Bakterielle Kontamination von Blutkomponenten

Montag

Lange

Schmidt

et al. 1999

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschu

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“…The speedy refrigeration of the filled bottle is not necessary in temperate climates and up to 8 hours may safely elapse before so doing [10]. In warmer climes it is sometimes the practice to take the blood into chilled A. C. D. solution but it is doubtful whether the initial lowering of the temperature of the collected blood has any beneficial effect and it may even discourage the anti-bacterial properties of the blood.…”

Section: Bacterial Contamination Of Preserved Bloodmentioning

confidence: 99%

“…The steps to be taken have been described [10] and where it is also pointed out that even if some hours have elapsed before culturing the suspected bottle, the presence of large numbers of organisms would mean almost certainly that the blood had been contaminated before the time of the transfusion and not during or subsequent to the transfusion, this opinion being based on experi ments which demonstrated the difficulty of producing a heavy growth of organisms in citrated blood by chance contamination.…”

Section: Bacterial Contamination Of Preserved Bloodmentioning

confidence: 99%

Bacterial Contamination of Preserved Blood

James¹

1959

Vox Sanguinis

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Effect of Temperature on Survival of Bacteria in Blood for Transfusion

Cited by 26 publications

References 10 publications

Blood Replacement

Blood Replacement

Bakterielle Kontamination von Blutkomponenten

Bacterial Contamination of Preserved Blood

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