“…Disregarding the immediately-or delayed-loading types, dislocation of the implant may lead to failure to the replacement procedure and imposes clinical and financial costs to the patients. The stability of a dental implant closely relies on either the endogenic (like bone quality, vasculature, infective or inflammatory diseases, etc) or the exogenic (loading type, implant design, life style, etc) conditions [4][5][6][7][8][9][10]. Low bone quality is a most relevant reason that challenges the implantation success [11], and can reduce the implant stability due to the overall osteoporosis specifically for the aged patients or local lack of osteogenic cells at the boneimplant interface (BII) [12,13].…”