Effect of Substituents on Phenazine Derivatives by Spectral Studies

Abstract

A series of eleven substituted dipyrido[3,2-a; 2′,3′-c]phenazine derivatives have been synthesized and examined their purities by literature method. The infrared and 13C NMR spectral data of prepared phenazines were correlated with Hammett substituent constants, F and R parameters using single and multi-regression analysis. From the results of statistical analysis, the effect of substituents on the infrared frequencies (ν, cm-1) and 13C nmr chemical shifts(δ, ppm) has been studied.

Spectral LFER Studies on Some Sydnone Chalcones

“…Infrared spectra of synthesized (E)-4-(N-(4-cinnamoylphenyl)sulfamoyl)-3-(p-tolyl)-1,2,3oxadiazol-3-ium-5-olates, the characteristic stretches (ν, cm −1 ) of CO s-cis, s-trans , CH ip , op , CH=CH op , C=C op , NH, SO 2 , and CO syd have been assigned and tabulated in Table 1. Using Hammett equation and single and multi-regression analysis [13][14][15][16][20][21][22][23][24][25][26][27][28][29][30][31]of these data with Hammett substituent constants and Swain-Lupton's [33] parameters. In this correlation, the Hammett equation was taken in the form as (1).…”

“…Thirunarayanan and his co-workers have studied the effect of substituents on spectral data of some oxazine-2-amines [26]. The spectral correlation of infrared and carbon-13 NMR data of quinoxaline and phenazine derivatives were studied by Thirunaryanan et al [27,28]. Senbagam et al, have studied the effects of substituents on some substituted (E)-N-benzylidene-4H-1,2,4-triazol-4-amines [29].…”

Infrared, ¹H and ¹³C NMR Spectral Studies of some 4-([1,1′-Biphenyl]-4-yl)-6-(Substituted Phenyl)-5,6-Dihydro-4H-1,3-Oxazine-2-Amines: Assessment of Substituent Effects

“…From the infrared spectra of synthesized oxazine derivatives, the characteristic stretches (ν, cm −1 ) of NH 2 , C=N and C-O-C were assigned and tabulated in Table 1. Using Hammett equation and single and multi-regression analysis [2,[15][16][17][18][19][20][21][22][23][24] of these data with Hammett substituent constants and Swain-Lupton's [26] parameters, the obtained statistical results are tabulated in Table 2. From the Table 2, the NH 2 stretches (ν, cm −1 ) gave satisfactory correlations with positive ρ values.…”

“…From 13 C NMR spectra, the chemical shifts (δ, ppm) of C=N, and C 4-6 carbons were assigned and are tabulated in Table 1. These chemical shifts were correlated with Hammett σ, σ + , σ I , σ R constants F and R parameters using single and multi-parameter regression analysis [2,[15][16][17][18][19][20][21][22][23][24]. The results of single and multi-parameter statistical analyses are presented in Table 2.…”

“…Proton nuclear magnetic resonance spectroscopic data were applied for prediction of Eand Zconformations of unsaturated systems and spatial arrangements of cyclic systems [20]. Thirunarayanan et al, have studied the infrared and NMR spectral correlations of phenazine and quinoxaline derivatives [21,22]. Mayavel et al, have studied the spectral correlation of some E-imines [23].…”