Effect of subinhibitory concentrations of cumin (Cuminum cyminum L.) seed essential oil and alcoholic extract on the morphology, capsule expression and urease activity of Klebsiella pneumoniae

Derakhshan, Safoura; Sattari, Morteza; Bigdeli, Mohsen

doi:10.1016/j.ijantimicag.2008.05.009

Cited by 89 publications

(67 citation statements)

References 12 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Growth of K. pneumoniae strains exposed to sub-MICs of Cuminum cyminum extracts resulted in cell elongation and repression of capsule expression. Urease activity was decreased [221].…”

Section: Cyminum Cuminummentioning

confidence: 95%

Medicinal plants with antimicrobial activities (part 2): Plant based review

Al-Snafi¹

2016

SAJP

View full text Add to dashboard Cite

“…Growth of K. pneumoniae strains exposed to sub-MICs of Cuminum cyminum extracts resulted in cell elongation and repression of capsule expression. Urease activity was decreased [221].…”

Section: Cyminum Cuminummentioning

confidence: 95%

Medicinal plants with antimicrobial activities (part 2): Plant based review

Al-Snafi¹

2016

SAJP

View full text Add to dashboard Cite

“…Urease activity was determined according to the method described by Derakhshan et al (2008). Urea broth containing sub-MIC and MIC levels of eugenol and linalool was used for cultivation of bacterial strains overnight.…”

Section: Effect Of Sub-mic and Mic Levels Of Eugenol And Lialool On Bmentioning

confidence: 99%

Eugenol and linalool: Comparison of their antibacterial and antifungal activities

El-Baky¹,

Hashem²

2016

Afr. J. Microbiol. Res.

View full text Add to dashboard Cite

Antimicrobial resistance is one of the greatest threats to human health. Alternatives to antimicrobials are needed to combat the rise of bacterial resistance. Essential oils (EOs) and their components are potential sources of new antimicrobials. The present study was conducted to evaluate the antibacterial and antifungal activities of two components of EOs. The antimicrobial mechanisms of eugenol and linalool were investigated against five bacterial strains and four Candida strains. Broth macrodilution method was used to compare the antibacterial and anticandidal activities of the two compounds. They exhibited antimicrobial activity against all tested strains. Germ tube formation by Candida albicans was investigated and it was found that it was completely inhibited at sub-MICs of eugenol while linalool showed minor activity compared to eugenol. Time kill kinetic studies indicated that eugenol was highly toxic to all bacterial and fungal strains within 2.5 h of exposure. Absorbance of intracellular constituents was measured at 260 nm. Only eugenol was highly effective toward lysis and cellular content leakage compared to control drugs. In addition, scanning electron microscopy (SEM) was used to charactize the effect of the two components on cell morphology and showed that both compounds induced cellular deformity of nearly all tested cells. Also, it was found that only eugenol inhibited the Beta-lactamase production and urease activity and it diminished bacterial motility of all tested bacterial strains. These results indicate that eugenol and linalool are effective antimicrobial agents and both antibacterial and antifungal activities of linalool were much weaker than that of eugenol.

show abstract

“…Both samples showed activity against S. aureus, P. multocida and E. coli. [105] Beside exerting bacteriostatic and bactericidal effects EOs are also capable of impairing the development of capsules [137] and spores. [138] Cuminum cyminum L. (Apiaceae) is, on the one hand, a popular spice and, on the other hand, it is traditionally applied for its astringent and carminative effects.…”

Section: Essential Oils Against Gram-positive and Gram-negative Humanmentioning

confidence: 99%

A review on recent research results (2008–2010) on essential oils as antimicrobials and antifungals. A review.

Lang

Buchbauer

2011

Flavour & Fragrance J

340

209

View full text Add to dashboard Cite

The antimicrobial activity of essential oils is discussed in this review taking in account studies which were published in the period of time from 2008 until September 2010. Furthermore, the most important methods to examine the antimicrobial efficiency of essential oils are presented. The studies are divided into the following two groups, namely antibacterial and antifungal active agents depending on the activity of the applied essential oil against the test microorganisms. Various interesting possible applications are revealed such as the use of essential oils instead of synthetic drugs to circumvent the increasing resistance of some pathogens. Moreover, they could not only be used for the therapy of infectious illnesses, but also as preservatives in the food industry. A further possibility is, among others, the application of essential oils in skin products in order to treat or avoid dermal infections. Additionally, the prevalent constituents of the individual antimicrobial active essential oils are elaborated.

show abstract

Effect of subinhibitory concentrations of cumin (Cuminum cyminum L.) seed essential oil and alcoholic extract on the morphology, capsule expression and urease activity of Klebsiella pneumoniae

Cited by 89 publications

References 12 publications

Medicinal plants with antimicrobial activities (part 2): Plant based review

Medicinal plants with antimicrobial activities (part 2): Plant based review

Eugenol and linalool: Comparison of their antibacterial and antifungal activities

A review on recent research results (2008–2010) on essential oils as antimicrobials and antifungals. A review.

Contact Info

Product

Resources

About