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“…Harrison 8 quotes Dale's statement that "so far as our experi¬ mental trials have proceeded there is no indication that dis¬ solving the neoarsphenamine preparation before injection in a 2.5 per cent solution of sodium thiosulfate has any deleterious effect on the therapeutic action of the particular preparation on trypanosomiasis in mice." Voegtlin and Dyer9 reported that large doses of sodium thiosulfate did not decrease the trypanocidal efficiency of arsphenamine, neoarsphenamine or sulfarsphenamine and did not decrease the spirocheticidal action of sulfarsphenamine.…”
Section: Activity Of Arsenicalsmentioning
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“…Harrison 8 quotes Dale's statement that "so far as our experi¬ mental trials have proceeded there is no indication that dis¬ solving the neoarsphenamine preparation before injection in a 2.5 per cent solution of sodium thiosulfate has any deleterious effect on the therapeutic action of the particular preparation on trypanosomiasis in mice." Voegtlin and Dyer9 reported that large doses of sodium thiosulfate did not decrease the trypanocidal efficiency of arsphenamine, neoarsphenamine or sulfarsphenamine and did not decrease the spirocheticidal action of sulfarsphenamine.…”
Section: Activity Of Arsenicalsmentioning