Effect of Sodium Humate on the Content of Trace Elements in Organs of Weaned Piglets

Zralý, Z.; Písaříková, B.

doi:10.2754/avb201079010073

Cited by 10 publications

(10 citation statements)

References 28 publications

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“…Although HSs can combine with metal ions, oxides and clay to form water-soluble or insoluble complexes and can interact with organic compounds (Boyd et al, 1981;Livens, 1991;Islam et al, 2005), only a few studies have investigated the specific effects of FA or HA on the intestinal absorption of trace elements (Willis, 2015) and on the trace element concentrations in different organs of piglets (Zraly and Pisarikova, 2010) and rats (Cagin et al, 2016).…”

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confidence: 99%

Effect of fulvic and humic acids on iron and manganese homeostasis in rats

Szabó

Vucskits²,

Berta

et al. 2017

Acta Veterinaria Hungarica

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The objective of this study was to investigate the effects of fulvic acid (FA) and humic acid (HA) as the two main compounds of humic substances, separately on Fe and Mn homeostasis. Seventy-two male Wistar rats were randomly divided into 9 experimental groups. The control diet (AIN-93G formula) and diets supplemented with 0.1%, 0.2%, 0.4% and 0.8% HA or FA were fed for 26 days. Fe and Mn concentrations of the large intestinal content, liver, kidney, femur and hair were determined. No significant differences were observed in the production parameters. The effects of FA and HA on iron homeostasis were significantly different. FA proved to be a good iron source, and slightly increased the iron content of liver and kidney, but -up to a dietary iron level of 52.7 mg/kg -it did not influence the efficiency of iron absorption. Above a dietary iron level of 52.7 mg/kg down-regulation of Fe absorption can be assumed. HA significantly stimulated the iron uptake and there was no down-regulation of Fe absorption up to 0.8% dietary HA supplementation level (61.5 mg Fe/kg diet). In the HA groups the iron content of the liver and kidney decreased significantly, suggesting that in spite of the better Fe absorption, the HA-Fe complex does not provide iron to the investigated organs. Neither FA nor HA supplementation influenced the Fe content of the femur and hair and slightly decreased the Mn concentration in the large intestinal content. This effect was significant (with a 22.7% Mn concentration decrease) only at the HA supplementation rate of 0.8%. Neither FA nor HA influenced significantly the Mn concentrations of the liver, kidney and femur. The Mn concentration of the hair in rats receiving FA-or HA-supplemented diets was higher than in the control rats; however, this result needs further confirmation.

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confidence: 99%

Effect of fulvic and humic acids on iron and manganese homeostasis in rats

Szabó

Vucskits²,

Berta

et al. 2017

Acta Veterinaria Hungarica

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“…Increased concentrations of blood serum glucose, triacylglycerols (P < 0.01), calcium and iron (P < 0.05) were detected in experimental vs. control piglets. The results of the present study indicated that despite a positive effect, sodium humate caused a decrease in concentration of physiologically important manganese and selenium in the tissues [12].…”

Section: Application Of Probiotic "Stimix Zoostim" In Calves Managementmentioning

confidence: 41%

The use of humic acids in livestock

Качепа

Маниесон

Васильев

et al. 2019

asj

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state agrarian university named after N.I. Vavilov MANIESON Victor Emmanuel, Saratov state agrarian university named after N.I. Vavilov VASILIEV Alexey Alexeevich, Saratov state agrarian university named after N.I. Vavilov SIVOKHINA Lyubov Alekcandrovna, Saratov state agrarian university named after N.I. Vavilov The article presents the literature data on the results of the use of humic acids and substances derived from them as feed additives for pigs. Some ways of application of humic acids in feeding of pigs and data of the previous researches are described. At the end of the article the conclusion about the influence of humic acids on the productivity and safety of pigs is considered, the proposals for further more advanced scientific research are given.

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“…We observed a tendency to increase the calcium content with age in young rabbits of the experimental and control groups. Several possible mechanisms of the effect of humic additive on calcium absorption have been described (Zralý et al, 2010;Trckova et al, 2018). Humic acid additives are known for their chelating properties, which are due to the presence of carboxyl and hydroxyl functional groups in them.…”

Section: Discussionmentioning

confidence: 99%

“…The literature includes statements about ambiguity of the effect of humic additive on the calcium content in the blood. A number of researchers have noted an increase in serum calcium in piglets when humic additive is added to their main diet (Zralý et al, 2010;Trckova et al, 2018). But an increase in the blood calcium was not observed in the studies of humic additive in rabbits and birds (Stepchenko et al, 1991;Mista et al, 2012).…”

Section: Discussionmentioning

confidence: 99%

“…It is possible that iron absorption increases due to the intensification of calcium absorption, because it is a non-competitive inhibitor of the DMT-1 transporter, which moves iron to the basolateral surface of the enterocyte (Shawki & Mackenzie, 2010;Beck et al, 2017). Literature data point out that humic acid additive increases blood iron levels (Ipek et al, 2008;Zralý et al, 2010;Mista et al, 2012). Ipek et al (2008) note an increased iron content in the blood of Japanese quail.…”

Section: Discussionmentioning

confidence: 99%

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The impact of humic acid additives on mineral metabolism of rabbits in the postnatal period of ontogenesis

Hunchak

Martynyshyn

Gutyj

et al. 2020

Regul. Mech. Biosyst.

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Humic acids are characterized by chelating properties due to which they are able to influence the mineral metabolism in animals. Rabbits have species-specific characteristics of mineral metabolism, which distinguishes them from most species of mammals. For the experiment, 16 rabbits of 45-day-old of Hyplus breed were divided into the experimental and control group of 8 rabbits in each. The animals were 15 days in the preparatory period. The rabbits of the experimental group received humic acid additive individually with water in the amount of 5 mg/kg, the rabbits of the control group received pure water in the same amount. The ability of humic acid additive to increase the content of calcium, ionized calcium, iron, to correct the content of copper and zinc, and also to increase the activity of alkaline phosphatase in the blood serum of rabbits of the experimental group has been proved. We observed the early effect of the humic acid additive on increasing the content of iron and calcium ionized and a later effect on the activity of alkaline phosphatase and an increase in the content of copper in the blood serum. The influence of humic acid additive on the distribution of calcium, phosphorus, manganese, copper and zinc in bone tissue is determined. According to a histological study, there was a significant increase in the number of layers of osteons and osteoblasts in the bone tissue of the femur, an increase in the number of osteons and osteoblasts in the bone tissue of the sternum and an increase in the number of columns of chondrocytes and an increase in the number of chondrocytes in the column in the cartilaginous tissue of the sternum. The results of a histological study of bone tissue, together with an increase in structural macroelements in it and redistribution of osteotropic trace elements in the blood and bone tissue suggest the possibility of using a humic acid additive to intensify the growth and mineralization of bone tissue, which can improve the state of bone tissue of rabbits in the postnatal period ontogenesis.

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Effect of Sodium Humate on the Content of Trace Elements in Organs of Weaned Piglets

Cited by 10 publications

References 28 publications

Effect of fulvic and humic acids on iron and manganese homeostasis in rats

Effect of fulvic and humic acids on iron and manganese homeostasis in rats

The use of humic acids in livestock

The impact of humic acid additives on mineral metabolism of rabbits in the postnatal period of ontogenesis

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