Effect of probiotic and prebiotic inclusion in weaned piglet diets on structure and ultra-structure of small intestine

Budiño, Fábio Enrique Lemos; Thomaz, Maria Cristina; Kronka, Rodolfo Nascimento; Nakaghi, Laura Satiko Okada; Tucci, Fernanda Marcussi; Fraga, Alessandro Luís; Scandolera, Antônio João; Huaynate, Rizal Alcides Robles

doi:10.1590/s1516-89132005000800008

Cited by 35 publications

(32 citation statements)

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“…Studies prior to 2006 indicate that health strategies widely used antibiotic growth promoters to reduce enteric infections and the occurrence of pathogens able to adhere to intestinal mucosa (Budino et al, 2005). Among a variety of candidates for the replacement of antibiotics, organic acids have been broadly applied worldwide with reasonable success (Mroz, 2005).…”

Section: Introductionmentioning

confidence: 99%

Analysis of the effect of dietary protected organic acid blend on lactating sows and their piglets

2016

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-The objective of the present study was to evaluate the effects of blends of dietary protected organic acid supplementation on growth performance, nutrient digestibility, blood profiles, faecal microflora, and gas emission on sows and piglets with emphasis on their modes of action to improve pig performance. A total of 12 sows with an average initial body weight (BW) of 252.40±11.7 kg were used in this trial. Growth performance, blood profiles, and nutrient digestibility of sows and piglets fed protected organic acid were evaluated. The dietary treatments included a basal diet (CON); CON + 0.1% protected organic acid; and CON + 0.2% protected organic acid. The BW and back fat of sows was checked four days prior to farrowing and at the weaning day to calculate BW loss and back fat loss during that period. Inclusion of 0.2% protected organic acid provided a greater digestibility than CON diets throughout the experimental period in lactating sows. Dietary supplementation with 0.2% protected organic acid led to a higher white blood cell and lymphocyte concentration than CON treatment in sucking piglets. Immunoglobulin G concentration observed was greater in protected organic acid groups in lactating sow and sucking piglets. Increased faecal Lactobacillus counts with decreased E. coli concentrations were observed with the diets of protected organic acid fed to lactating sows. The E. coli counts were decreased in weaning piglets. The faecal H 2 S contents were decreased in 0.2% protected organic acid diets during farrowing on day 1. Dietary supplementation with protected organic acid blends beneficially affects the nutrient digestibility, ileal noxious gas (NH 3 and H 2 S) emission, as well as intestinal microbial balance in lactating sows.

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Section: Introductionmentioning

confidence: 99%

Analysis of the effect of dietary protected organic acid blend on lactating sows and their piglets

2016

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“…5, 6 e 7), o que se deveu ao aumento no diâmetro destes. Essa diminuição da densidade dos vilos, em função do aumento da idade dos animais, também foi observada em frangos de corte, por Maiorka et al (2000), e em leitões desmamados, por Budiño et al (2005).…”

Section: Resultsunclassified

“…Cera et al (1988) observaram redução na altura dos microvilos do jejuno de leitões, entre três e sete dias após o desmame. Budiño et al (2005) também não observaram diferenças na altura dos microvilos no duodeno e jejuno em leitões suplementados com prebiótico (FOS). Os aditivos estudados não alteraram (P>0,05) o desempenho dos leitões após o desmame (Tab.…”

Section: Resultsunclassified

Efeito da adição de agentes tróficos na dieta de leitões desmamados sobre a estrutura e ultraestrutura do intestino delgado e sobre o desempenho

Tucci

Thomaz

Nakaghi

et al. 2011

Arq. Bras. Med. Vet. Zootec.

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“…In a study investigating weaned piglets, Budiño et al (2005) administered a feed without additives and a feed containing an antibiotic, a probiotic, a prebiotic and a synbiotic to discover that the density and length of duodenal villi was higher in pigs fed a diet with the prebiotic than in those receiving a diet with the probiotic. The above authors also concluded that in comparison to diets containing other additives, the structure and efficiency of intestinal villi were restored at a much faster rate in pigs administered the probiotic.…”

Section: Discussionmentioning

confidence: 99%

“…Researchers vary in their opinions on the probiotic effect of bacteria on the intestinal epithelium. Baum et al (2002) and Budiño et al (2005) demonstrated that Saccharomyces boulardii and Bacillus cereus var. Toyoi strains had a beneficial influence on the epithelial structure, crypt morphology, number of Ki-67 positive cells and total mucosal cell counts, including cells secreting acidic and neutral mucopolysaccharides.…”

Section: Feed Additives Fatteners Small Intestine Goblet Cells Bamentioning

confidence: 99%

The Effect of Probiotics on the Morphological Characteristics of the Small Intestinal Mucosa

2010

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The objective of this study was to determine the impact of antibiotics and selected probiotics on the morphological properties of the small intestinal mucosa in growing-finishing pigs. Two production experiments were conducted on 32 hybrid fatteners (16 pigs per experiment, of 8 gilts and young hogs each, at a 1:1 ratio) fed complete diets in a 2-phase system. The animals were clinically healthy and had been treated for parasites prior to fattening. In the first experiment, diets were supplemented with the antibiotic flavomycin (group C1) and the probiotic ToyoCerin (Bacillus toyoi strain) (group E1) at the amount of 0.1%, and in the second experiment with flavomycin (C2) and Bactocell (Pedicoccus acidilactici, MA18/5M strain) (E2) at the amount of 0.01%. A histological analysis of small intestinal epithelial sections was performed using bax, bcl-x, bcl-2 polyclonal antibodies and Ki-67 and PCNA monoclonal antibodies. Sections of the duodenum, jejunum and ileum were prepared post mortem. Haematoxylin and eosin H-E, histochemical (PAS-Alcian Blue) and immunohistochemical staining procedures were applied. The results of histological, histochemical and immunohistochemical examinations of the small intestinal mucosa indicated that feed additives and probiotics had a varied effect on the morphological characteristics and the proliferation capacity of crypt epithelium. Enterocyte proliferation in crypt epithelium decreased after the administration of probiotics. The absence of significant differences between groups (C1-E1; C2-E2) may suggest that probiotics have no adverse effect on mucosal epithelial cells. Nevertheless, given the importance of this topic and the development of the use of feed additives, follow up research in this area is needed. Feed additives, fatteners, small intestine, goblet cells, bax, bcl-x, bcl-2, PCNA, Ki-67Nutritional factors and bacterial populations colonizing the gastrointestinal tract modify the intestinal microstructure (Vitini et al. 2000) and induce functional changes in the intestinal mucosa (Babinska et al. 2005). Researchers vary in their opinions on the probiotic effect of bacteria on the intestinal epithelium. Baum et al. (2002) and Budiño et al. (2005) demonstrated that Saccharomyces boulardii and Bacillus cereus var. Toyoi strains had a beneficial influence on the epithelial structure, crypt morphology, number of Ki-67 positive cells and total mucosal cell counts, including cells secreting acidic and neutral mucopolysaccharides. Reiter (2006) did not observe any changes in the small and large intestine as a result of the supplementation of diets fed to sows and piglets with Enterococcus faecium strains. Lodemann et al. (2006) found that probiotics had a positive effect on animals. The findings of Pérez-Conesa et al. (2007) who studied rats administered probiotics, prebiotics and synbiotics indicate that feed additives significantly modify the depth of crypts in the proximal and distal colonic segments, and improve calcium, magnesium and phosphorus absorption. Rekiel et...

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Effect of probiotic and prebiotic inclusion in weaned piglet diets on structure and ultra-structure of small intestine

Abstract: ABSTRACT

Cited by 35 publications

References 5 publications

Analysis of the effect of dietary protected organic acid blend on lactating sows and their piglets

Analysis of the effect of dietary protected organic acid blend on lactating sows and their piglets

Efeito da adição de agentes tróficos na dieta de leitões desmamados sobre a estrutura e ultraestrutura do intestino delgado e sobre o desempenho

The Effect of Probiotics on the Morphological Characteristics of the Small Intestinal Mucosa

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