Effect of pharmaceutical care intervention on blood pressure of elderly outpatients with hypertension

Júnior, Divaldo Pereira de Lyra; Marcellini, Paulo Sérgio; Pelá, Irene Rosemir

doi:10.1590/s1516-93322008000300015

Cited by 20 publications

(18 citation statements)

References 29 publications

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“…The two summary measures are the Physical Component Summary and the Mental Component Summary score. Items scores related to each subscale are coded, summed, and scaled from 0 (worst possible health state) to 100 (best possible health state) [23,33,35,36]. The MLHFQ is one of the most widely used questionnaires to evaluate quality of life of patients with HF.…”

Section: Methodsmentioning

confidence: 99%

Impact of pharmaceutical care on the quality of life of patients with Chagas disease and heart failure: randomized clinical trial

Silva

Chambela

Sousa

et al. 2012

Trials

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BackgroundPharmaceutical care is the direct interaction between pharmacist and patient, in order to improve therapeutic compliance, promote adequate pharmacotherapeutic follow-up, and improve quality of life. Pharmaceutical care may be effective in reducing complications and in improving the quality of life of patients with chronic diseases, like Chagas heart disease, while bringing a positive impact on health system costs. The morbidity and mortality indexes for patients with Chagas heart disease are high, especially if this heart disease is complicated by heart failure. In this setting, we hypothesize that pharmaceutical care might be an important tool for the clinical management of these patients by improving their quality of life, as a better compliance to their treatment and the avoidance and prompt correction of drug-related problems will minimize their symptoms, improve their functional class, and decrease the number of hospital admissions. Therefore, the aim of this trial is to evaluate the contribution of pharmaceutical care to clinical treatment of patients with Chagas heart disease complicated by heart failure.Methods/designA prospective, single-center randomized clinical trial will be conducted in patients with Chagas heart disease complicated by heart failure. A total of 88 patients will be randomly assigned into two parallel groups: an intervention group will receive standard care and pharmaceutical care, and a control group will receive only standard care. Both groups will be subjected to a follow-up period of 12 months. The primary outcome of this trial is the evaluation of quality of life, measured by the 36-item short-form and the Minnesota Living with Heart Failure Questionnaire. Secondary outcomes include drug-related problems, exercise tolerance as measured by the standard six-minute-walk test, and compliance.DiscussionPatients with Chagas heart disease complicated by heart failure under pharmaceutical care are expected to improve their quality of life, present with a lower incidence of drug-related problems, improve their functional capacity, and improve in their compliance to treatment.Trial registrationClinicalTrials.gov Identifier: NCT01566617

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Section: Methodsmentioning

confidence: 99%

Impact of pharmaceutical care on the quality of life of patients with Chagas disease and heart failure: randomized clinical trial

Silva

Chambela

Sousa

et al. 2012

Trials

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show abstract

“…Pharmacists in developing countries work mainly in activities related to acquisition and inventory control of drugs, with little involvement in direct patient care (Obreli Neto et al, 2011). There are a few published studies on the clinical outcomes of this practice in Brazil, mainly in the primary care setting (Mourão et al, 2013;Obreli Neto et al, 2011;Obreli Neto, Cuman, 2010;Lyra Júnior, Marcellini, Pelá, 2008;de Souza et al, 2007;.…”

Section: Introductionmentioning

confidence: 99%

Clinical outcomes of medication therapy management services in primary health care

Mendonça

Melo

Pereira

et al. 2016

Braz. J. Pharm. Sci.

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This study evaluates whether the integration of pharmacists into health-care teams through the delivery of pharmaceutical care-based medication therapy management (MTM) services can improve the clinical outcomes of patients with chronic health conditions in the primary health-care setting. A retrospective descriptive study of 92 outpatients assisted by MTM pharmacists in primary health-care units was carried out over 28 months (median follow-up: 05 months). Patients were followed up by MTM pharmacists, with a total of 359 encounters and a ratio of 3.9 encounters per patient. The prevalence of hypertension, diabetes mellitus and dyslipidaemia was 29.5%, 22.0% and 19.4%, respectively. There was a high prevalence of drug-related problems with a ratio of 3.4 per patient. Pharmacists performed a total of 307 interventions to prevent or resolve drug-related problems. With regard to control of the most prevalent chronic medical conditions, a high percentage of patients reached their therapy goals by the last encounter with the pharmacist: 90.0% for hypertension, 72.3% for diabetes mellitus and 90.3% for dyslipidaemia. MTM services provided by pharmacists resolved drug therapy problems and improved patients' clinical outcomes. This study provides evidence for health-care managers of the need to expand the clinical role of pharmacists within the Brazilian public health-care system. Uniterms: Pharmaceutical care/primary care. Medication therapy management. Chronic health/ conditions. Pharmacists/professional practice/Brazil

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“…Previous pharmaceutical care studies developed in developing countries have involved small samples [13], were nonrandomized [14,15], were of small duration [13][14][15] and did not report pharmacotherapy adherence rates [14][15][16]. It has been suggested that rigorously designed pharmaceutical care studies addressing pharmacotherapy adherence are of paramount importance [11,12].…”

Section: Introductionmentioning

confidence: 99%

Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients

et al. 2011

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Effect of pharmaceutical care intervention on blood pressure of elderly outpatients with hypertension

Cited by 20 publications

References 29 publications

Impact of pharmaceutical care on the quality of life of patients with Chagas disease and heart failure: randomized clinical trial

Impact of pharmaceutical care on the quality of life of patients with Chagas disease and heart failure: randomized clinical trial

Clinical outcomes of medication therapy management services in primary health care

Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients

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