Effect of pH on the Micellar Properties of a Nonionic Surfactant

Deconvolution procedure of the UV–vis spectra. A powerful tool for the estimation of the binding of a model drug to specific solubilisation loci of bio-compatible aqueous surfactant-forming micelle

“…As for the micellization process at physiological pH conditions, presence of hydroxide ions which act as structure-makers by exalting the hydrophobic effect induces the self-organisation of the polysorbate biosurfactant at very low concentration. Moreover, analogues pH trends have been reported for the Tween 40 aqueous solutions [16].…”

Effect of cinnamic acid on phase transition and pH-dependent release property of monoolein cubic phase

“…As the pH value is lower, the concentration of oxonium ion is higher. At a lower pH value, the hydroxyl groups of a non-ionic surfactant were more hydrated with water molecule [20]. Likewise, at a lower pH value, the hydroxyl groups of MO would be more hydrated and they would be less subjected to the hydrogen bonding among themselves.…”

Pickering particle and emulsifier co-stabilised emulsions produced via rotating membrane emulsification

“…Although in general non-ionic emulsifiers are considered to be pH insensitive, it is reported that the hydration rate of Tween molecules (initial concentration 0.02%) dissolved in aqueous medium at pH 2 was almost four times higher than pH 6.5 [50]. Furthermore in another study it was shown that increasing the pH of non-ionic Tween 40 would cause less hydration per unit mass of surfactant and the critical micelle concentration is decreased considerably which means more surfactant micelles in the aqueous solution [51]. Consequently, it is possible that the availability of Tween molecules for adsorption at low pH was increased causing faster reduction of the interfacial tension and thus smaller drops.…”