Effect of palmitate, acetate and glucose on glutamine metabolism in Ehrlich ascites tumor cells

Highly Glycolytic Immortalized Human Dermal Microvascular Endothelial Cells are Able to Grow in Glucose-Starved Conditions

“…During the last century, uptake and utilization of different metabolic substrates were tested in the presence of these different metabolic fuels alone or in combination, using tumor cell lines or healthy cell lines [51,52,53,54,55]. Nevertheless, few studies were carried out under these conditions in ECs [11,56,57,58].…”

Highly Glycolytic Immortalized Human Dermal Microvascular Endothelial Cells are Able to Grow in Glucose-Starved Conditions

“…During the last century, uptake and utilization of different metabolic substrates were tested in the presence of these different metabolic fuels alone or in combination, using tumor cell lines or healthy cell lines [51,52,53,54,55]. Nevertheless, few studies were carried out under these conditions in ECs [11,56,57,58].…”

Metabolic Reprogramming is a Hallmark of Metabolism Itself

“…[ 1 ] Indeed, we now know that cancer not only has altered metabolism of glucose and glutamine, but also that of other amino acids, fatty acids, cholesterol, and polyamines. [ 32–40 ] In recent years there has been an increasing number of articles analyzing the reprogramming of metabolism in different types of cancer—as well as its potential for targeting—or papers describing the role of specific drivers of such a reprogramming. [ 41–60 ]…”

Highly Glycolytic Immortalized Human Dermal Microvascular Endothelial Cells are Able to Grow in Glucose-Starved Conditions

“…During the last century, uptake and utilization of different metabolic substrates were tested in the presence of these different metabolic fuels alone or in combination, using tumor cell lines or healthy cell lines [51,52,53,54,55]. Nevertheless, few studies were carried out under these conditions in ECs [11,56,57,58].…”

Metabolic Reprogramming is a Hallmark of Metabolism Itself

“…[ 1 ] Indeed, we now know that cancer not only has altered metabolism of glucose and glutamine, but also that of other amino acids, fatty acids, cholesterol, and polyamines. [ 32–40 ] In recent years there has been an increasing number of articles analyzing the reprogramming of metabolism in different types of cancer—as well as its potential for targeting—or papers describing the role of specific drivers of such a reprogramming. [ 41–60 ]…”

Highly Glycolytic Immortalized Human Dermal Microvascular Endothelial Cells are Able to Grow in Glucose-Starved Conditions

“…During the last century, uptake and utilization of different metabolic substrates were tested in the presence of these different metabolic fuels alone or in combination, using tumor cell lines or healthy cell lines [51,52,53,54,55]. Nevertheless, few studies were carried out under these conditions in ECs [11,56,57,58].…”

Metabolic Reprogramming is a Hallmark of Metabolism Itself

“…[ 1 ] Indeed, we now know that cancer not only has altered metabolism of glucose and glutamine, but also that of other amino acids, fatty acids, cholesterol, and polyamines. [ 32–40 ] In recent years there has been an increasing number of articles analyzing the reprogramming of metabolism in different types of cancer—as well as its potential for targeting—or papers describing the role of specific drivers of such a reprogramming. [ 41–60 ]…”