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Cited by 159 publications
(139 citation statements)
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“…Talc is the most commonly used pleurodesis agent and a meta-analysis supports its use as the sclerosant of choice [4,75]. Even within the context of large randomised trials, pleurodesis success rates remain under 80% and are almost certainly lower in everyday practice [9,10,76,77]. It has been proven that graded preparations (as opposed to small particle talc) should be used to minimise systemic talc particle dissemination and the risk of acute respiratory distress syndrome [78,79].…”
Section: Pleurodesismentioning
confidence: 99%
See 3 more Smart Citations
“…Talc is the most commonly used pleurodesis agent and a meta-analysis supports its use as the sclerosant of choice [4,75]. Even within the context of large randomised trials, pleurodesis success rates remain under 80% and are almost certainly lower in everyday practice [9,10,76,77]. It has been proven that graded preparations (as opposed to small particle talc) should be used to minimise systemic talc particle dissemination and the risk of acute respiratory distress syndrome [78,79].…”
Section: Pleurodesismentioning
confidence: 99%
“…Even today, no consensus exists about the optimal size of the chest drain and the time of removal of the tube post-pleurodesis. National guidelines advocate the use of small bore (<14 F) chest drains, but this is now challenged by the results of the largest study to specifically address tube size for MPE in terms of pleurodesis success [10]. Specifically, the TIME1 study showed that smaller chest tubes might be inferior to larger ones in terms of pleurodesis success [10].…”
Section: Pleurodesismentioning
confidence: 99%
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“…The management of malignant pleural effusions has seen considerable progress within the past decade, with a number of randomised controlled trials now informing practice [1][2][3]. This progress, by contrast, has not been mirrored in non-malignant pleural disease, which has an evidence base still formed largely of observational studies.…”
Section: Introductionmentioning
confidence: 99%